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Human CD16-/CD66b+ Eosinophils-Negatively Selected

Product Name

Human CD16-/CD66b+ Eosinophils-Negatively Selected

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Cat.No

ABC-TC4372

Species

Human

Size/Quantity

1M

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Eosinophils are bone marrow-derived granulocytes that represent about 5% of leukocytes in peripheral blood. Activated eosinophils are involved in defense against parasitic, bacterial, and viral infections and play an important role in promoting allergic inflammatory processes, including asthma. Eosinophils are characterized by bilobed nuclei and large specific granules. These cytotoxic granules are composed of four major proteins: eosinophil peroxidase, major basic protein (MBP), eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN). CD66b, also called CEACAM8, is a highly expressed protein on eosinophils, which regulates the adhesion and activation of eosinophils by interaction with galectin-3 and CD11b.

Why choose Human CD16-/CD66b+ Eosinophils-Negatively Selected from AcceGen?

Human CD16-/CD66b+ eosinophils-negatively selected are isolated from peripheral blood using AcceGen’s negative immunomagnetic separation techniques. Cells are cryopreserved to ensure the best viability. Each vial contains more than 1×10^6 cells in 1ml volume.

Disease

Normal

Quality Control

All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Human CD16-/CD66b+ eosinophils provide a readily accessible model for studying the biology and pathophysiology of eosinophils. Eosinophils are involved in a wide variety of diseases, including asthma, eosinophilic gastrointestinal (GI) disease and hypereosinophilic syndrome. A further investigation targeting eosinophils may provide valuable insights into an eosinophil-associated disease treatment.

Key Features

– Backed by AcceGen advanced technology

– Cryopreserved for highest viability and plating efficiency

– Quality-guaranteed for accurate results

– Timely technical support for best experimental outcomes

Growth Conditions

37 ℃, 5% CO2

Cell Type

Eosinophil

Product Type

Immune Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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