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H520

Product Name

H520

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Product Code

H520; H-520; NCI-HUT-520; NCIH520

Cat.No

ABC-TC527S

Species

Human

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Derived from a lung mass of a patient with squamous cell carcinoma, the H520 cell line demonstrates a significant reduction in p53 mRNA expression compared to normal lung tissue. This human hypotriploid cell line displays a modal chromosome count of 58 in approximately 30% of its cells, devoid of major structural DNA abnormalities. While exhibiting positive keratin and vimentin staining, it shows no presence of neurofilament triplet protein. Impressively, these cells exhibit the capability to create colonies in soft agar and initiate tumor growth within a mere 21 days in nude mice.

 

Why choose H520 from AcceGen?

The H520 cell line from AcceGen showcases remarkable viability and quality, having satisfactorily cleared rigorous quality control assessments. It maintains sterility and is devoid of bacterial, fungal, mycoplasma, and human pathogen presence, including HIV, HBV, and HCV. Furthermore, the cells are cryopreserved using advanced techniques.

Disease

Squamous Cell Cancer

Source Organ

Lung

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The H520 cell line finds crucial applications in probing chemotherapy sensitivity and resistance to anticancer treatments. Its utility extends to the exploration of innovative therapies like antiproliferative drugs, assessment of the inhibitory impact of small ribonucleic acids (siRNA) on cell proliferation and invasion, as well as evaluating the efficacy of anticancer agents in inducing apoptosis.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Human Lung Cancer Cell Lines

Product Image

AcceGen Frozen Cells & Cell Lines

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