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MicroRNA sponge is encoded by plasmid, which can be easily purified from E.Coli instead of the cost and complex chemical synthesis;

MicroRNA sponge is particularly valuable for long-term loss-of-function study both in vitro and in vivo.

MicroRNA sponge expression cassette can be engineered into genome by generation of stable cell lines;

Through deliberately designing of microRNA sponge, a whole family of miRNAs can be silenced;

Even completely unrelated miRNAs binding sequences can be constructed compatibly within one vector, so microRNA sponge could     slience multiple miRNAs simultaneously.

Multiple options for miRNA sponge vectors: non-viral/viral plasmid backbone, promoter, reporter gene, antibiotic selection marker,tandem repeat number etc.

Cost effective and fast turnaround time.

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