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Human Peripheral Blood Mononuclear Cells (PBMCs)

Peripheral Blood Mononuclear Cells (PBMC), also known as Human Mononuclear Cells from Peripheral Blood (HMNC-PB), are cells possessing a single, round nucleus and are collected from the peripheral or circulating blood.These blood cells are a critical component in the immune system to fight infection and adapt to intruders. PBMCs give selective responses to the immune system and are the major cells in the human body immunity.

As a mixed population of single nucleus cells, PBMCs mainly comprise of lymphocytes, including T cells, B cells, and natural killer (NK) cells. PMBCs are also a rich source of monocytes, such as macrophages, dendritic cells. Further cell isolations are carried out by selecting key protein surface markers such as CD4+ (T helper cells), CD8+ (cytotoxic T cells), CD14+ (monocytes).

PBMCs are separated from peripheral blood by density centrifugation using ficoll, a hydrophilic polysaccharide. The whole blood can be separated into a top layer of plasma, followed by a lower layer of PBMCs, then a fraction of polymorphonuclear cells (such as neutrophils and eosinophils), and finally a bottom layer of erythrocytes. This highly pure population of cells makes them ideal for further isolations of specific cell types within the PBMC fraction.

AcceGen PBMCs Superiorities
- Over 500 different lots available
- Isolated from both healthy and diseased individuals
- Cryopreserved immediately after isolation
- Stored in frozen vials

AcceGen offers PBMC products and keeps the inventory updated to meet customers’ needs. For more information about PBMCs or any other AcceGen products, please call us at 1-862-686-2696 or send an email to Your questions and requests will be answered by expert staff in AcceGen within 24 hours.

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Normal PBMCs

Diseased PBMCs

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