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Knockin Stable Cell Lines

AcceGen Knockin Stable Cell Lines

CRISPR/Cas9-induced site-specific DNA double-strand breaks (DSBs) can be repaired by homology-directed repair (HDR) or non-homologous end joining (NHEJ) pathways. Extensive efforts have been made to knock-in exogenous DNA to a specific genomic locus via the HDR pathway in mammalian cells.

As an experienced company in cell engineering, AcceGen provides reliable, affordable, and fast knock-in cell line generation service, which includes gRNA/donor DNA construction, engineered cell line generation, and PCR sequencing.

Our experienced scientists have working with various cells ranging from easy-to-transfect cell lines (tumor cell line) to hard-to-transfect cells (primary cells). So, we can provide high-quality knock-in cell lines to meet your requirements.

AcceGen knockin cell lines generation workflow

Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

Cat.# Name Description Stock Price

ABC-KH4653

Human EGFR (S492R/+/+) SW48 Cell Line

Human EGFR (S492R/+/+) SW48 Cell line is Heterozygous knockin of EGFR S492R mutation in cis configur...more

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ABC-KH4652

Human EGFR (L861Q/+) RKO Cell Line

Human EGFR (L861Q/+) RKO Cell line is Heterozygous knockin of EGFR activating mutation (L861Q). ...more

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ABC-KH4651

Human EGFR (L861Q/+) MCF10A Cell Line

Human EGFR (L861Q/+) MCF10A Cell line is Heterozygous knockin of EGFR activating mutation (L861Q). ...more

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ABC-KH4650

Human EGFR (L858R/+/+) SW48 Cell Line

Human EGFR (L858R/+/+) SW48 Cell line is Heterozygous knockin of EGFR activating mutation (L858R). ...more

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ABC-KH4649

Human EGFR (L858R/+) RKO Cell Line

Human EGFR (L858R/+) RKO Cell line is Heterozygous knockin of EGFR activating mutation (L858R). ...more

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ABC-KH4648

Human EGFR (L858R/+) NCI-H838 Cell Line

Human EGFR (L858R/+) NCI-H838 Cell line is Heterozygous knockin of EGFR activating mutation (L858R)....more

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ABC-KH4647

Human EGFR (L858R/+) MCF10A Cell Line

Human EGFR (L858R/+) MCF10A Cell line is Heterozygous knockin of EGFR activating mutation (L858R). ...more

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ABC-KH4646

Human EGFR (L65V/+/+) SW48 Cell Line

Human EGFR (L65V/+/+) SW48 Cell line is Heterozygous knockin of EGFR point mutation (L65V). ...more

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ABC-KH4645

Human EGFR (I491M/+/+) SW48 Cell Line

Human EGFR (I491M/+/+) SW48 Cell line is Heterozygous knockin of EGFR I491M mutation in cis configur...more

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ABC-KH4644

Human EGFR (C240Y/+) RKO Cell Line

Human EGFR (C240Y/+) RKO Cell line is Heterozygous knockin of EGFR point mutation (C240Y). ...more

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ABC-KH3722

Human CTNNB1 (T41A/+/+) MCF10A Cell Line

Human CTNNB1 (T41A/+/+) MCF10A Cell line is Heterozygous knockin of CTNNB1 activating mutation. ...more

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ABC-KH3032

Human CHEK1 (S317A/-) TP53 (S241F/sil) DLD-1 Cell Line

Human CHEK1 (S317A/-) TP53 (S241F/sil) DLD-1 Cell line is Heterozygous knockin of phosphorylation si...more

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ABC-KH2830

Human CDK2 (D145N/D145N) HCT116 Cell Line

Human CDK2 (D145N/D145N) HCT116 Cell line is Homozygous knockin of CDK2 dominant negative mutation (...more

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ABC-KH2829

Human CDK2 (D145N/+) HCT116 Cell Line

Human CDK2 (D145N/+) HCT116 Cell line is Heterozygous knockin of CDK2 dominant negative mutation (D1...more

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ABC-KH1549

Human BRCA2 (Y3308X/-) DLD-1 Cell Line

Human BRCA2 (Y3308X/-) DLD-1 Cell line is Heterozygous knockin of BRCA2 inactivating point mutation ...more

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ABC-KH1548

Human BRCA2 (S3291E/-) DLD-1 Cell Line

Human BRCA2 (S3291E/-) DLD-1 Cell line is Heterozygous knockin of BRCA2 hypomorphic point mutation a...more

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ABC-KH1545

Human BRCA1 (185delAG/+) MCF10A Cell Line

Human BRCA1 (185delAG/+) MCF10A Cell line is Heterozygous knockin of 2-bp deletion in BRCA1 resultin...more

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ABC-KH1542

Human BRAF (V600R/+) HCT116 Cell Line

Human BRAF (V600R/+) HCT116 Cell line is Heterozygous knockin of BRAF activating mutation (V600R). ...more

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ABC-KH1541

Human BRAF (V600M/+) HCT116 Cell Line

Human BRAF (V600M/+) HCT116 Cell line is Heterozygous knockin of BRAF mutation (V600M). ...more

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ABC-KH1540

Human BRAF (V600K/+) MCF10A Cell Line

Human BRAF (V600K/+) MCF10A Cell line is Heterozygous knockin of BRAF activating mutation (V600K). ...more

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