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Knockout Stable Cell Lines

AcceGen Knockout Stable Cell Lines

The CRISPR/Cas9 system has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).

CRISPR-Cas9 is a genome-editing tool that is creating a buzz in the science world. It is faster, cheaper and more accurate than previous techniques of editing DNA and has a wide range of potential applications. Our scientists use the CRISPR CAS9 (CRISPR/Cas9) to knock out one or double genes to generate a KO cell line.

AcceGen is offering a series of gene knockout cell lines developed by the CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions. Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

Cat.#NameDescriptionStockPrice

ABC-KH17977

Human ESR1 Mutant cell line

ESR1 Mutant cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17976

Human VHL knockout cell line

Human VHL knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17975

Green Monkey NECTIN1 knockout cell line

Green Monkey NECTIN1 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17974

Human AP1S1 knockout cell line

Human AP1S1 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17973

Human SNORA59B knockout cell line

Human SNORA59B knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17972

Human SMG6 knockout cell line

Human SMG6 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17971

Pig KLF4 knockout cell line

Pig KLF4 knockout cell line is edited by CRISPR/Cas9 technology. ...more

Custom

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ABC-KH17970

Rat KLF4 knockout cell line

Rat KLF4 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17969

Mouse CD115 knockout cell line

Mouse CD115 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17968

Mouse IL17RA knockout cell line

Mouse IL17RA knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17967

Mouse TUT1 knockout cell line

Mouse TUT1 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17966

Mouse AK2 knockout cell line

Mouse AK2 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17965

Human TING knockout cell line

Human TING knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17964

Human LOC100270804 knockout cell line

Human LOC100270804 knockout cell line is edited by CRISPR/Cas9 technology. ...more

Custom

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ABC-KH17963

Human IL17RA knockout cell line

Human IL17RA knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17962

Human LINC00944 knockout cell line

Human LINC00944 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17961

Human RAPSYN knockout cell line

Human RAPSYN knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17960

Human BRCA2 knockout cell line

Human BRCA2 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17959

Human TANGO6 knockout cell line

Human TANGO6 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17958

Human BRCA2 knockout cell line

Human BRCA2 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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