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Knockout Stable Cell Lines

AcceGen Knockout Stable Cell Lines

The CRISPR/Cas9 system has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).

CRISPR-Cas9 is a genome-editing tool that is creating a buzz in the science world. It is faster, cheaper and more accurate than previous techniques of editing DNA and has a wide range of potential applications. Our scientists use the CRISPR CAS9 (CRISPR/Cas9) to knock out one or double genes to generate a KO cell line.

AcceGen is offering a series of gene knockout cell lines developed by the CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions. Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

Cat.# Name Description Stock Price

ABC-KH17957

Human MCM10 knockout cell line

Human MCM10 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17956

Human MCM10 knockout cell line

Human MCM10 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17955

Human UCA1 knockout cell line

Human UCA1 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17954

Human RSRP1 knockout cell line

Human RSRP1 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17953

Human RSRP1 knockout cell line

Human RSRP1 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17952

Human PKM2 knockout cell line

Human PKM2 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17951

Human RNF20 knockout cell line

Human RNF20 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17950

Human DMT1 knockout cell line

Human DMT1 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17949

Human P2Y2 knockout cell line

Human P2Y2 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17948

Human JMJD3 knockout cell line

Human JMJD3 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17947

Human PBXIP knockout cell line

Human PBXIP knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17946

Human PXR knockout cell line

Human PXR knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17945

Human CAR knockout cell line

Liquid Nitrogen Human CAR knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17944

Human INMAP knockout cell line

Human INMAP knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17943

Human P75NTR knockout cell line

Human P75NTR knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17942

Human P53 knockout cell line

Human P53 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17941

Human IGF1R knockout cell line

Human IGF1R knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17940

Rat RGLP1R knockout cell line

Rat RGLP1R knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17939

Chinese Hamster AGO2 knockout cell line

Chinese Hamster AGO2 knockout cell line is edited by CRISPR/Cas9 technology. ...more

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ABC-KH17938

Green monkey GSDME knockout cell line

Green monkey GSDME knockout cell line is edited by CRISPR/Cas9 technology. ...more

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