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Knockin Stable Cell Lines

AcceGen Knockin Stable Cell Lines

CRISPR/Cas9-induced site-specific DNA double-strand breaks (DSBs) can be repaired by homology-directed repair (HDR) or non-homologous end joining (NHEJ) pathways. Extensive efforts have been made to knock-in exogenous DNA to a specific genomic locus via the HDR pathway in mammalian cells.

As an experienced company in cell engineering, AcceGen provides reliable, affordable, and fast knock-in cell line generation service, which includes gRNA/donor DNA construction, engineered cell line generation, and PCR sequencing.

Our experienced scientists have working with various cells ranging from easy-to-transfect cell lines (tumor cell line) to hard-to-transfect cells (primary cells). So, we can provide high-quality knock-in cell lines to meet your requirements.

AcceGen knockin cell lines generation workflow

Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

Cat.#NameDescriptionStockPrice

ABC-KH7142

Human IDH2 (R140Q/+) HCT116 Cell Line

Human IDH2 (R140Q/+) HCT116 Cell line is Heterozygous knockin of IDH2 mutation (R140Q) implicated in...more

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ABC-KH7140

Human IDH1 (R132H/+) MCF10A Cell Line

Human IDH1 (R132H/+) MCF10A Cell line is Heterozygous knockin of IDH1 dominant-negative (R132H) poin...more

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ABC-KH7139

Human IDH1 (R132H/+) HCT116 Cell Line

Human IDH1 (R132H/+) HCT116 Cell line is Heterozygous knockin of IDH1 dominant-negative (R132H) poin...more

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ABC-KH7138

Human IDH1 (R132C/+) HCT116 Cell Line

Human IDH1 (R132C/+) HCT116 Cell line is Heterozygous knockin of IDH1 mutation (R132C) implicated in...more

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ABC-KH6994

Human HRAS (G12V/+) SW48 Cell Line

Human HRAS (G12V/+) SW48 Cell line is Heterozygous knockin of HRAS activating mutation (G12V). ...more

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ABC-KH6181

Human GNAS (R201C/+) SW48 Cell Line

Human GNAS (R201C/+) SW48 Cell line is Heterozygous knockin of GNAS activating mutation R201C. ...more

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ABC-KH6180

Human GNAS (R201C/+) HCT116 Cell Line

Human GNAS (R201C/+) HCT116 Cell line is Heterozygous knockin of GNAS activating mutation (R201C). ...more

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ABC-KH6178

Human GNAQ (Q209L/+) HCT116 Cell Line

Human GNAQ (Q209L/+) HCT116 Cell line is Heterozygous knockin of GNAQ activating mutation (Q209L). ...more

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ABC-KH6167

Human GNA11 (Q209L/+) HCT116 Cell Line

Human GNA11 (Q209L/+) HCT116 Cell line is Heterozygous knockin of GNA11 activating mutation (Q209L)....more

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ABC-KH5607

Human FLT3 (ΔI836/+) HCT116 Cell Line

Human FLT3 (ΔI836/+) HCT116 Cell line is Heterozygous knockin of FLT3 activating mutation (ΔI836). ...more

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ABC-KH5606

Human FLT3 (D835Y/+) HCT116 Cell Line

Human FLT3 (D835Y/+) HCT116 Cell line is Heterozygous knockin of FLT3 activating mutation (D835Y). ...more

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ABC-KH5536

Human FGFR3 (S249C/+) HCT116 Cell Line

Human FGFR3 (S249C/+) HCT116 Cell line is Heterozygous knockin of FGFR3 activating mutation (S249C)....more

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ABC-KH5534

Human FGFR2 (S252W/+/+) HCT116 Cell Line

Human FGFR2 (S252W/+/+) HCT116 Cell line is Heterozygous knockin of FGFR2 activating mutation (S252W...more

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ABC-KH4661

Human EGFR (ΔE746-A750/+) PIK3CA (H1047R/+) MCF10A Cell Line

Human EGFR (ΔE746-A750/+) PIK3CA (H1047R/+) MCF10A Cell line is Double heterozygous knockin of EGFR ...more

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ABC-KH4660

Human EGFR (ΔE746-A750/+) RKO Cell Line

Human EGFR (ΔE746-A750/+) RKO Cell line is Heterozygous knockin of EGFR activating mutation (ΔE746-A...more

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ABC-KH4659

Human EGFR (ΔE746-A750/+) NCI-H838 Cell Line

Human EGFR (ΔE746-A750/+) NCI-H838 Cell line is Heterozygous knockin of EGFR activating mutation (ΔE...more

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ABC-KH4658

Human EGFR (ΔE746-A750/+) MCF10A Cell Line

Human EGFR (ΔE746-A750/+) MCF10A Cell line is Heterozygous knockin of EGFR activating mutation (ΔE74...more

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ABC-KH4656

Human EGFR (T790M/+) RKO Cell Line

Human EGFR (T790M/+) RKO Cell line is Heterozygous knockin of EGFR mutation (T790M) conferring drug ...more

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ABC-KH4655

Human EGFR (T790M/+) MCF10A Cell Line

Human EGFR (T790M/+) MCF10A Cell line is Heterozygous knockin of EGFR mutation (T790M) conferring dr...more

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ABC-KH4654

Human EGFR (S768I/+) RKO Cell Line

Human EGFR (S768I/+) RKO Cell line is Heterozygous knockin of EGFR point mutation (S768I). ...more

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