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STAT3 Knockout Cell Lysate

Product Name

STAT3 Knockout Cell Lysate

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Cat.No

ABC-KC1981

Species

Human

Size/Quantity

100ug

Shipping Info

Ice Pack

Storage

Store STAT3 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Description

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]

Stock

Custom

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Host Cell

HeLa

Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Growth Mode

Adherent

Product Type

CRISPR Knockout Cell Lysate

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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