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Knockout Stable Cell Lines

AcceGen Knockout Stable Cell Lines

The CRISPR/Cas9 system has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).

CRISPR-Cas9 is a genome-editing tool that is creating a buzz in the science world. It is faster, cheaper and more accurate than previous techniques of editing DNA and has a wide range of potential applications. Our scientists use the CRISPR CAS9 (CRISPR/Cas9) to knock out one or double genes to generate a KO cell line.

AcceGen is offering a series of gene knockout cell lines developed by the CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions. Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

Cat.#NameDescriptionPrice

ABC-KH1144

Human ATG5 knockout cell line

Human ATG5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17916

CH12F3 (APE1-/-/-APE2-) Cell Line

CH12F3 is capable of cytokine-induced Ig heavy chain CSR. Key enzymes involved in DNA recombination ...more +inquiry

ABC-KH16870

Human WAC knockout cell line

Human WAC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16890

Human WBSCR28 knockout cell line

Human WBSCR28 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16908

Human WDR31 knockout cell line

Human WDR31 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16928

Human WDR6 knockout cell line

Human WDR6 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16947

Human WDR86 knockout cell line

Human WDR86 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16966

Human WFDC12 knockout cell line

Human WFDC12 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16986

Human WI2-2373I1.2 knockout cell line

Human WI2-2373I1.2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17007

Human WNK4 knockout cell line

Human WNK4 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17026

Human WNT8A knockout cell line

Human WNT8A knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17045

Human WWC1 knockout cell line

Human WWC1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17065

Human XCR1 knockout cell line

Human XCR1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17084

Human XKRX knockout cell line

Human XKRX knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17100

Human XRCC5 (+floxed/-) HCT116 Cell Line

Human XRCC5 (+floxed/-) HCT116 Cell line is Knockout of single XRCC5 allele and flanking of exon 3 i...more +inquiry

ABC-KH17116

Human YEATS2 knockout cell line

Human YEATS2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17132

Human YPEL4 knockout cell line

Human YPEL4 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17148

Human ZAN knockout cell line

Human ZAN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17164

Human ZBTB14 knockout cell line

Human ZBTB14 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17180

Human ZBTB37 knockout cell line

Human ZBTB37 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry
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