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Knockout Stable Cell Lines

AcceGen Knockout Stable Cell Lines

The CRISPR/Cas9 system has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).

CRISPR-Cas9 is a genome-editing tool that is creating a buzz in the science world. It is faster, cheaper and more accurate than previous techniques of editing DNA and has a wide range of potential applications. Our scientists use the CRISPR CAS9 (CRISPR/Cas9) to knock out one or double genes to generate a KO cell line.

AcceGen is offering a series of gene knockout cell lines developed by the CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions. Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.

Cat.#NameDescriptionPrice

ABC-KH1144

Human ATG5 knockout cell line

Human ATG5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17916

CH12F3 (APE1-/-/-APE2-) Cell Line

CH12F3 is capable of cytokine-induced Ig heavy chain CSR. Key enzymes involved in DNA recombination ...more +inquiry

ABC-KH16875

Human WASF2 knockout cell line

Human WASF2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16894

Human WDFY4 knockout cell line

Human WDFY4 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16913

Human WDR38 knockout cell line

Human WDR38 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16933

Human WDR63 knockout cell line

Human WDR63 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16952

Human WDR90 knockout cell line

Human WDR90 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16971

Human WFDC5 knockout cell line

Human WFDC5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH16991

Human WIPF2 knockout cell line

Human WIPF2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17011

Human WNT11 knockout cell line

Human WNT11 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17030

Human WRAP53 knockout cell line

Human WRAP53 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17050

Human WWP1 knockout cell line

Human WWP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17070

Human XIAP (-/Y) DLD-1 Cell Line

Human XIAP (-/Y) DLD-1 Cell line is Knockout of X-linked XIAP allele in male parental cells ...more +inquiry

ABC-KH17088

Human XPC knockout cell line

Human XPC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17104

Human XRCC6BP1 knockout cell line

Human XRCC6BP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17120

Human YIPF1 knockout cell line

Human YIPF1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17136

Human YTHDF3 knockout cell line

Human YTHDF3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17152

Human ZBBX knockout cell line

Human ZBBX knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17168

Human ZBTB20 knockout cell line

Human ZBTB20 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry

ABC-KH17184

Human ZBTB40 knockout cell line

Human ZBTB40 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. ...more +inquiry
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