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Human Retinal Pigment Epithelial Cells

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Human Retinal Pigment Epithelial Cells

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1 vial

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Dry Ice


Liquid Nitrogen


Human retinal pigment epithelial (HRPE) cells are isolated from human retinal pigment tissue with the digestion by collagenase. They are a single layer of densely packed regular polygonal cells, filled with pigment granules, and positioned at the outermost layer of the retina. Within the HRPE cells, microvillous structures extend between photoreceptor outer segments (POS), contributing to the HRPE’s phagocytic function. The integrity and functionality of the HRPE are crucial, as any impairment can give rise to a range of retinopathies,  for which effective treatments are currently lacking. Moreover, damage to RPE cells is closely associated with numerous retinal degenerative conditions, including age-related macular degeneration, retinitis pigmentosa, and Stargardt’s disease.


Why choose Human Retinal Pigment Epithelial Cells from AcceGen?

AcceGen’s Human retinal pigment epithelial (HRPE) cells offer several advantages. They are cryopreserved at passage one and guaranteed to expand for 10 population doublings. AcceGen also provides optimized medium and reagents, ensuring maximum performance for in vitro HRPE cell culture. This comprehensive solution offers researchers a reliable and efficient system for studying the development, function, and pathobiology of the retinal pigment epithelium. With AcceGen’s HRPE cells, researchers can confidently conduct their studies, benefiting from the high-quality cells and optimized culture conditions provided by a trusted supplier.



Source Organ


Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).



Understanding the normal function of HRPE cells and their role in retinal diseases is crucial for preventing and treating retinopathies. The HRPE is a vital layer of cells between the retina and choroid, responsible for maintaining retinal health and performing essential functions. By studying HRPE cells, we gain insights into the development, function, and pathobiology of the HRPE, enabling us to address conditions such as age-related macular degeneration, retinitis pigmentosa, diabetic retinopathy, photoreceptor degeneration, gene expression, and cellular interactions. These investigations provide valuable knowledge for improving diagnosis, understanding disease mechanisms, and developing effective therapeutic interventions.


Growth Conditions

37 ℃, 5% CO2

Cell Type


Growth Mode


Product Type

Ocular Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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