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Human Retinal Pigment Epithelial Cells

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Human Retinal Pigment Epithelial Cells

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1 vial

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Dry Ice


Liquid Nitrogen


The human retina is a multi-layered structure lining the rear of the eye. It consists of photoreceptor cells and retinal pigment epithelial cells (RPE). RPE situated between the neurosensory retina and the choroid, form the outer blood-retina barrier that controls the chemical composition of the subretinal space. RPE has long been recognized to differ from many other epithelia in the polarity of a number of proteins and whereas almost all other epithelia face an apical lumen devoid of matrix, the RPE apical plasma membrane is in contact with the extracellular matrix. During early embryonic development, RPE spontaneously transdifferentiate into neural retinal tissue. RPE play a critical role in the development and maintenance of adjacent photoreceptors. They generate a number of reactive oxygen species when illuminated with light and their proliferation is an important step in the pathogenesis of ocular diseases such as proliferative retinopathy. HRPEpiC from AcceGen Research Laboratories are isolated from human retina. HRPEpiC are cryopreserved at passage one and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HRPEpiC are characterized by immunofluorescent method with antibodies to cytokeratin-18, cytokeratin-19 and fibronectin. HRPEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HRPEpiC are guaranteed to further expand for 15 population doublings in the condition provided by AcceGen Research Laboratories.

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

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When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).


For research use only

Product Type

Ocular Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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