Human Type II Alveolar Epithelial Cells

Introduction to Type II Alveolar Cells
Human Type II Alveolar Epithelial Cells (PAEpiC2), also known as Type 2 Pneumocytes or AT2 Cells, are isolated from human lung tissue, playing a critical role in retaining the alveoli integrity and function. The Alveolar Type II Cells are specialized to produce surfactant, which reduces surface tension in the alveoli. ACE2 cells function in the repair process after lung injury by proliferating and spreading to cover the alveolar surface.

Applications of Type II Alveolar Cells
Study the pathogenic mechanism of lung disease samples from the cellular and molecular levels through the collection and identification of surface-active proteins.
The Type II Pneumocytes injury is found in some typical severe lung diseases, such as idiopathic pulmonary fibrosis. Study has proven that COVID-19 would affect alveolar epithelial cells. Therefore, AT2 Epithelial Cells is a good choice for COVID-19 research. Human Alveolar Type 2 cells are considered to have the potential to replace cell lines to study the repair mechanism.

Why Choose AT2 Cells from AcceGen?
Cells are derived from normal lung tissue, with over 90% purity.
Cells are negative in HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi.
Pulmonary surfactant protein A (SP-A) was positive by immunofluorescence staining.
Cryopreserved Human Pulmonary Alveolar Epithelial Cells are also available at AcceGen.