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Human Kidney Podocyte Cells
Human Kidney Podocyte Cells
The Human Kidney Podocyte Cells are primary cells isolated from human kidney. They are specialized cells located in the kidney glomerulus, enveloping capillaries and neighboring cells of the Bowman’s capsule. These cells actively participate in glomerular filtration by acting as a barrier against plasma proteins entering the urinary ultrafiltrate. This barrier is formed by filtration slits between their foot processes, which create a dynamic network of cellular extensions. Podocytes rely on vesicular transport, a significant process in their polarized nature. Injury to podocytes can lead to various kidney diseases, with the extent and reversibility of the injury carrying significant implications for treatment and prognosis. In a healthy state, podocytes play a crucial role in preventing proteinuria. However, they become susceptible targets for injury in different renal diseases, ultimately influencing the outcome.
Why choose Human Kidney Podocyte Cells from AcceGen?
Choosing Human Kidney Podocyte Cells from AcceGen offers the advantage of receiving cryopreserved cells at passage one, delivered frozen. With each vial containing over 500,000 viable cells, we provide a substantial cell population for experimentation. Furthermore, these cells are guaranteed to expand for up to 10 population doublings, ensuring an adequate supply of cells for research purposes, as long as the instructions provided in the technical sheet are followed.
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Podocytes cannot be cultured for more than 1 or 2 passage without loss of their particular traits (like foot processes and expression of slit diaphragm proteins).
|Recommended Medium And Supplement
ABM-H0004Y Human Kidney Podocyte Cells Medium Kit
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
Human Kidney Podocytes in culture offer a valuable in vitro model for investigating renal diseases. These cultured cells can be utilized in various applications such as toxicology studies to assess the potential toxicity of substances on kidney function. Additionally, they serve as a platform to study the metabolism of drugs and therapeutic targeting, aiding in the development of new treatments for renal diseases. Furthermore, human kidney podocytes in culture contribute to research and development efforts focused on understanding renal physiology, providing insights into the functioning of the kidney and potential interventions for various renal disorders.
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