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Immortalized Human Fibroblast-Like Synoviocyte Rheumatoid Arthritis

Product Name

Immortalized Human Fibroblast-Like Synoviocyte Rheumatoid Arthritis

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Cat.No

ABI-H0004X

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Immortalized cell lines, generated from primary cells, have an extended lifespan and provide a continuous and stable cell source for experimental purposes. Immortalized Human Fibroblast-Like Synoviocytes (FLS) in the context of rheumatoid arthritis (RA) refer to a type of cell found in the synovium, which is the tissue lining the joints. Immortalized Fibroblast-like synoviocytes are a key cell type involved in the pathogenesis of RA. Rheumatoid arthritis (RA) affects approximately 1% of the adult population1,2. Despite being a systemic disease, the primary clinical manifestations are synovitis and joint destruction. RA fibroblast-like synoviocytes (RA-FLS) play a central role in initiation and persistence of both synovitis and joint damage3,4.

Why choose Immortalized Human Fibroblast-Like Synoviocyte Rheumatoid Arthritis from AcceGen?

 

Rest assured, immortailized FLS cells undergo thorough testing to ensure premium quality. Negative results for mycoplasma, bacteria, yeast, and fungi guarantee the integrity of your experiments. Achieve unparalleled results with over 95% post-thaw viability, setting the stage for robust cell line performance. Witness optimal growth characteristics, meticulously validated through morphology assessments and immunocytochemistry of multiple undifferentiation markers. Immortalized Human FLS cell line is chosen for a seamless blend of reliability and excellence in advancing RA research.

Disease

Rheumatoid Arthritis

Source Organ

Synovium

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Immortalized Human Fibroblast-Like Synoviocyte Rheumatoid Arthritis can be used to investigate the behavior of synovial cells in the context of rheumatoid arthritis, including their responses to inflammatory stimuli, production of cytokines and other signaling molecules, and potential involvement in joint damage. Studying these cells helps researchers gain insights into the disease mechanisms and may contribute to the development of targeted therapies for rheumatoid arthritis.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Fibroblast-Like

Growth Mode

Adherent

Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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