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B-Lymphoblastoid Cell Lines (B-LCL)

Product Name

B-Lymphoblastoid Cell Lines (B-LCL)

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Cat.No

ABI-TC048D

Species

Human

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

B-Lymphoblastoid cell lines (B-LCL) are perpetually replicating B cell lines, originating from native B lymphocytes, that undergo transformation through Epstein-Barr virus (EBV) infection. These cell lines, established from peripheral blood samples, closely mimic activated B lymphocytes in terms of surface-expressed CD antigens. The transformative prowess of EBV lies in its ability to convert quiescent B-cells into self-sustaining, immortalized lymphoblastoid cells, retaining the virus in a latent state. This enables B-LCLs to persistently proliferate in vitro, providing valuable tools for research in immunology and virology.

 

Why choose B-Lymphoblastoid Cell Lines (B-LCL) from AcceGen?

AcceGen’s B-Lymphoblastoid Cell Lines (B-LCL) offer superior quality and viability. Prepared and incubated optimally by experts, our cells undergo rigorous mycoplasma screening and batch testing for sterility, count, viability, and authenticity using STR-PCR profiling, ensuring trustworthy and high-performance resources for your research.

Disease

Normal

Source Organ

Peripheral Lymph

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

B-Lymphoblastoid cell lines (B-LCL) stand out as an exceptionally versatile resource with a wide range of research applications. Offering a bountiful supply of intact cells or derived DNA, B-LCLs unlock extensive possibilities for studies encompassing molecular genetics and functional analyses. Their utility extends to immunological research, providing a convenient reservoir of antigen-presenting cells suitable for tasks like mixed lymphocyte reactions and presenting peptide antigens. Moreover, B-LCLs hold significant promise in the relatively novel arena of rare disease research, effectively circumventing the limitations of scarce native cellular/genetic materials by offering a readily available and perpetually renewable alternative.

Immortalization Method

Epstein-Barr virus (EBV)

Growth Conditions

37 ℃, 5% CO2

Cell Type

Lymphoblast

Growth Mode

Suspension

Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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