| Species |
CD1
|
| Cat.No |
ABC-TC145W
|
| Quality Control |
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
|
| Product Category |
Primary Cells |
| Size/Quantity |
1 vial
|
| Cell Type |
Neurons
|
| Shipping Info |
Dry Ice
|
| Growth Conditions |
37 °C, 5% CO2
|
| Source Organ |
Cerebellum
|
| Disease |
Normal
|
| Biosafety Level |
1
|
| Storage |
Liquid Nitrogen
|
| Product Type |
Cerebellar Granule Cells
|
Description
CD1 Cerebellar Granule Cells (CGCs) are primary neurons isolated from the cerebellum of CD1 mouse pups. In culture, they develop mature characteristics, such as an extensive network of neurites, expression of excitatory amino acid receptors, and synthesis and release of glutamate. CGCs rely on N-methyl-D-aspartate (NMDA) receptor activity for survival and differentiation both in vivo and in vitro. Functionally, CGCs integrate sensory and motor inputs via mossy fibers, relaying processed information to Purkinje cells, thereby fine-tuning motor coordination, learning, and cognitive functions. These cells are extensively used for studying neuronal apoptosis, ataxia, fetal alcohol spectrum disorders, and other neurodegenerative disease models.
