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Primary Cells

CD1 Cerebellar Granule Cells

  • For research use only

Cat No.

ABC-TC145W
Product Type

Cerebellar Granule Cells
Cell Type

Neurons
Species

CD1
Growth Conditions

37 °C, 5% CO2
Source Organ

Cerebellum
Disease

Normal
Storage

Liquid Nitrogen

CD1 Cerebellar Granule Cells (CGCs) are used for neurodevelopment, synaptic plasticity, neuroprotection, and modeling neurodegenerative diseases.

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  • CD1 Cerebellar Granule Cells
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Home | Primary Cells | Animal Primary Cells | CD1 Cerebellar Granule Cells

Description

CD1 Cerebellar Granule Cells (CGCs) are primary neurons isolated from the cerebellum of CD1 mouse pups. In culture, they develop mature characteristics, such as an extensive network of neurites, expression of excitatory amino acid receptors, and synthesis and release of glutamate. CGCs rely on N-methyl-D-aspartate (NMDA) receptor activity for survival and differentiation both in vivo and in vitro. Functionally, CGCs integrate sensory and motor inputs via mossy fibers, relaying processed information to Purkinje cells, thereby fine-tuning motor coordination, learning, and cognitive functions. These cells are extensively used for studying neuronal apoptosis, ataxia, fetal alcohol spectrum disorders, and other neurodegenerative disease models.

Species

CD1
Cat.No

ABC-TC145W
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Neurons
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Cerebellum
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Cerebellar Granule Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • CD1 Cerebellar Granule Cells (CGCs) are widely used to investigate neurodevelopment, synaptic plasticity, and neuroprotection mechanisms. They are valuable for modeling neurodegenerative diseases such as ataxia and fetal alcohol spectrum disorders. CGCs can be cultured to study excitatory receptor expression and glutamate synthesis, making them ideal for exploring neuronal survival mechanisms. Additionally, they provide a robust model for studying synaptic function and the molecular pathways involved in cerebellar development and degeneration.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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