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Cynomolgus Monkey Small Intestinal Epithelial Cells

Product Name

Cynomolgus Monkey Small Intestinal Epithelial Cells

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Cat.No

ABC-H0015Y

Species

Monkey

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Intestinal epithelial cells (IECs) are interconnected by tight junctions, forming a protective barrier in the gut that prevents the entry of harmful microorganisms, antigens, and toxins from the gut lumen into the bloodstream. The small intestinal epithelium primarily consists of terminally differentiated mucous and absorptive cells. While the small intestinal cells exhibit remarkable resistance to injury, any damaged cells undergo rapid apoptosis and are shed into the gut lumen. The replication and differentiation of intestinal epithelial cells exhibit distinct phenotypes, characterized by spatial boundaries. Cynomolgus monkeys have found extensive utility in predicting drug absorption in humans. AcceGen provides primary small intestinal epithelial cells derived from cynomolgus monkeys.

 

Why choose Cynomolgus Monkey Small Intestinal Epithelial Cells from AcceGen?

The Cynomolgus Monkey Small Intestinal Epithelial Cells from AcceGen guarantees sterility, being free from bacterial, fungal, Mycoplasma contamination, and human pathogens. These undifferentiated cells exhibit characteristic morphology and are verified using multiple undifferentiation markers through immunocytochemistry. These features make them a reliable and safe choice for research applications, facilitating the study of their biology, behavior, and differentiation potential in the context of intestinal health and regenerative medicine.

Disease

Normal

Source Organ

Intestine

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The application of cynomolgus monkey small intestinal epithelial cells holds significant potential in various fields related to intestinal health and regenerative medicine. By utilizing in vitro models of these cells, researchers can explore the regenerative capabilities of intestinal stem/progenitor cells and their potential in treating degenerative diseases such as colitis, inflammatory bowel disease, intestinal infections, and radiation injury. Understanding the factors and pathways involved in the controlled differentiation of stem/progenitor cells into tissue-specific lineages can greatly contribute to the development of effective clinical protocols. Moreover, studying the shedding of senescent enterocytes and the disturbance of intestinal homeostasis in inflammatory conditions can provide valuable insights into the underlying mechanisms and potential therapeutic interventions.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Monkey Primary Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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