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Human Splenic Endothelial Cells

Product Name

Human Splenic Endothelial Cells

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Product Code

HSEC

Cat.No

ABC-TC3817

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Spleen plays an important role in fighting blood born disease and filtering blood where pathogens, cellular debris and damaged and effete red blood cells are removed. Human splenic endothelial cells (HSEC) are one of the key components of the red pulp of the spleen. The endothelial cells loosely line the venous sinuses. They are connected by the stress fibers and arranged in parallel, which forms spleen specific interendothelial slits (IES) that forces blood to move from cords into the sinuses. The slit selectively allows passage of healthy red blood cells while aging red blood cells with stiffening membranes are filtered for phagocytosis.

Why choose Human Splenic Endothelial Cells from AcceGen?

AcceGen human splenic endothelial cells are isolated from fully consented healthy human spleen. HSEC cells at passage 1 are cryopreserved to ensure best viability. Each vial contains more than 5×10^5 cells. All cell lots are tested negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi and other pathogens. Human splenic endothelial cells are guaranteed for further expansion of at least 12 population doublings using AcceGen recommended cell culture media.

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Human spleen endothelial cells are similar to other endothelial cells where they maintain blood fluidity and regulate blood-tissue barrier. Splenic endothelial cells also have supportive role on the growth of dendritic cell in vitro and can be used to study endothelial cell-macrophage interaction. They are also useful tool for study myelofibrosis where the genetic profiling has revealed certain mutations of spleen endothelial cells are associated with the disease.

Key Features

-Backed by AcceGen advanced technology

-Cryopreserved for highest viability and plating efficiency

-Quality-tested for accurate results

-Expert teams to provide timely support and assist best experimental outcomes

Product Type

Spleen Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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