+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Nucleic Acid Kits
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Primary Cells

Human Type 2 Diabetes PBMCs

  • BSL

    1

  • 23
Request Your Custom Quote Today

Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.

Get a Quote
  • High Purity Levels
  • Precision and Reliability
  • Customization Options
Home | Primary Cells | Human Primary Cells | PBMCs | Human Type 2 Diabetes PBMCs
Species

Human
Cat.No

ABC-TC133W
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

PBMC
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Peripheral Blood
Disease

Type 2 Diabetes
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

PBMC

Description

Human Type 2 Diabetes (T2D) PBMCs are peripheral blood mononuclear cells derived from patients clinically diagnosed with type 2 diabetes. These cells exhibit heightened secretion of pro-inflammatory cytokines such as IFN-γ and TNF-α, demonstrate an imbalanced Th1/Th17 immune response, contributing to persistent low-grade inflammation known as metaflammation. Transcriptomic analyses reveal increased expression of macrophage-associated markers like IL12 and CCR7, as well as cholesterol transport-related genes such as ABCA1. Additionally, T2D PBMCs show impaired mitochondrial function, including reduced oxidative phosphorylation (OXPHOS) and weakened antioxidant defenses. These immunometabolic features make them an important ex vivo model for studying T2D pathophysiology, biomarker discovery, and therapeutic screening targeting inflammation and metabolism.

AcceGen Frozen Cells & Cell Lines 1 vial
View Product Image

Application

  • For research use only.

  • Human Type 2 Diabetes (T2D) PBMCs are widely applied in studies of chronic low-grade inflammation by analyzing cytokine secretion profiles and Th1/Th17 skewing, as well as in mitochondrial dysfunction research through evaluation of oxidative phosphorylation capacity and antioxidant enzyme expression. They are also used in transcriptomic studies to identify differential gene expression in response to metabolic stressors, and to assess the effects of therapeutic compounds such as metformin or GLP‑1 receptor agonists on immune cell phenotypes and inflammatory pathways.

  • Online Inquiry
  • Product Reviews

Inquiring Human Type 2 Diabetes PBMCs

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button