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Immortalized Human Fibroblasts

Product Name

Immortalized Human Fibroblasts

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1 vial

Shipping Info

Dry Ice


Liquid Nitrogen


Immortalized human fibroblasts, achieved through the introduction of Simian Virus 40 (SV40), are extensively utilized as a model in cell and molecular biology studies. These fibroblasts, which serve as crucial mediators in various biological processes such as inflammation, cancer, angiogenesis, and pathological tissue fibrosis, contribute significantly to the formation of connective tissue. As specialized cells, fibroblasts secrete collagen proteins, maintaining the structural integrity of tissues and facilitating their interconnectedness. Moreover, they play a pivotal role in the healing of wounds. It should be noted that SV40-immortalized human fibroblasts may potentially serve as a source of SV40 infection, as discussed in certain scientific literature.


Why choose Immortalized Human Fibroblasts from AcceGen?

Choosing immortalized human fibroblasts from AcceGen offers several advantages. AcceGen ensures that the fibroblasts are professionally operated under safe and optimal conditions, resulting in a sterile product. Their professional cryopreservation techniques maintain high viability, while rigorous quality control measures guarantee the reliability and consistency of the fibroblasts, making them a trusted choice for research and experimentation.



Source Organ

Connective Tissue

Quality Control

Real Time PCR was used to quantify SV40 gene expression in immortalized cell line.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).



Immortalized human fibroblasts find extensive applications in various fields of research. They are commonly employed in studies focused on wound healing, where their ability to secrete collagen proteins aids in understanding the underlying mechanisms. Additionally, these fibroblasts play a crucial role in tissue engineering and regeneration applications, contributing to the development of innovative approaches for repairing damaged tissues. Furthermore, they provide valuable support in the growth and establishment of induced pluripotent stem (iPS) cells, enhancing our understanding of cell reprogramming and regenerative medicine. Their versatility and significance make them indispensable tools in advancing these areas of scientific investigation.

Immortalization Method

Serial passaging and transduction with recombinant lentiviruses carrying SV40 Large T antigen

Growth Conditions

37 ℃, 5% CO2

Cell Type


Growth Mode


Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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