Primary Cells

Rhesus Monkey PBMCs

  • For research use only

Cat No.

ABC-HP028X

Product Type

Monkey Primary Cells

Cell Type

Monocyte

Species

Monkey

Growth Conditions

37 ℃, 5% CO2

Disease

Normal

Storage

Liquid Nitrogen

Rhesus Monkey PBMCs provide translational immune insights via T/B/NK cells and monocytes for studies on infection, vaccines, and immunotherapy.

Product Image

Description

Rhesus Monkey (Macaca mulatta) Peripheral Blood Mononuclear Cells (PBMCs) are isolated from healthy, colony-raised donors, providing an essential translational model for human immunology research. These PBMCs contain characteristic populations of T lymphocytes (CD3⁺, CD4⁺, CD8⁺), B cells (CD20⁺), NK cells (CD16⁺), and monocytes (CD14⁺), maintaining native morphology and functionality. The cells demonstrate conserved immune responses with human-like MHC class I and class II expression patterns, making them particularly valuable for infectious disease research including HIV/SIV, tuberculosis, and malaria studies. They exhibit robust proliferative capacity and cytokine production (IFN-γ, IL-2, IL-6) upon antigen stimulation. Additionally, these primate PBMCs isolated from rhesus monkey blood provide a critical resource for studying immune responses alongside rhesus monkey whole blood, dermal tissue, kidney epithelial cells, and hepatocytes in comprehensive translational research models.

Product Code

Rhesus Monkey PBMCs, RhPBMCs, Rhesus PBMC, Rhesus Monkey Peripheral Blood Mononuclear Cells

Species

Monkey

Cat.No

ABC-HP028X

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Monocyte

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Disease

Normal

Storage

Liquid Nitrogen

Product Type

Monkey Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Rhesus monkey PBMCs serve as critical tools for HIV/SIV vaccine development and pathogenesis studies due to their close immunological similarity to humans. These cells are widely used for preclinical evaluation of immunotherapies and adoptive cell transfer approaches. Researchers utilize them for MHC tetramer analysis of antigen-specific T cell responses in vaccine studies. Their human-like immune responses make them particularly valuable for comparative immunology studies bridging rodent and human data. Additionally, they are essential for modeling emerging infectious diseases including COVID-19 and Zika virus infection.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What are Peripheral Blood Mononuclear Cells (PBMCs)?

    Peripheral Blood Mononuclear Cells (PBMCs) are blood cells that have a single round nucleus. These cells include lymphocytes (such as T cells, B cells, and NK cells), monocytes, and dendritic cells. PBMCs play a crucial role in the immune system and are extensively used in research fields like immunology, infectious diseases, and hematological malignancies.

  • Why are rhesus macaques commonly used in biomedical research?

    Rhesus macaques are one of the most commonly utilized non-human primates in biomedical research due to their physiological similarities to humans. They are employed in various research areas such as immunology, neuroscience, oncology, infectious disease, and toxicology, making them valuable models for studying human diseases and developing treatments.

  • In which research fields are Rhesus Monkey PBMCs used?

    Rhesus Monkey PBMCs are widely used in research fields including immunology, where they help study immune responses; infectious diseases, where they aid in understanding pathogen-host interactions; hematological malignancies for exploring blood cancers; and other areas like neuroscience, oncology, and toxicology.

  • What cell types are included in Rhesus Monkey PBMCs?

    Rhesus Monkey PBMCs consist of several types of immune cells, including lymphocytes (T cells, B cells, and NK cells), monocytes, and dendritic cells. Each of these cell types plays a distinct role in the immune system, contributing to the body’s defense mechanisms and research applications.

  • How can researchers utilize Rhesus Monkey PBMCs in their studies?

    Researchers can utilize Rhesus Monkey PBMCs to investigate various aspects of the immune system, study the effects of infectious agents, develop and test new therapies for hematological malignancies, and explore the physiological responses in fields such as neuroscience, oncology, and toxicology. These cells provide a valuable tool for understanding disease mechanisms and evaluating potential treatments.

  • What are peripheral blood mononuclear cells?

    PBMCs are blood cells characterized by a single round nucleus, including lymphocytes and monocytes, and are typically CD45-positive immune cells.

  • What cells are in PBMCs?

    PBMCs consist primarily of T lymphocytes, B lymphocytes, natural killer (NK) cells, and monocytes, which together mediate adaptive and innate immune responses.

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