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Stem Cell Differentiation Service
With years of experience in stem cell research, AcceGen’s stem cell service team provides a variety of stem cell differentiation services for you. Our team consists of world-renowned scientific and technical experts who will closely collaborate with you throughout the entire process, starting from the initial design to the final delivery. We are dedicated to providing you with high-quality cells or organoids for your research and drug development needs.
How would you like the ideal outsourced scientific project to be? We envision ourselves as your collaborative partners, serving as both bench scientists and project managers, dedicated to supporting and expediting your research. Our goal is to work closely with you, side by side, to guarantee the success of your project. We value efficiency and effectiveness, just like you do, and we strive to achieve timely and high-quality results. We believe in maintaining clear and open lines of communication throughout the entire process.
Advantages:
- High-quality project outcomes
- Cost-effective
- No genetic footprint
- Tailred to your needs
Avaliable Features for your customized service
Differentiation from normal/disease cells
- Normal cells
- Disease cells
Sourcing of your starting stem cells
- Pick from one of AcceGen’s stem cells
- Provide your own stem cells
Type of your starting stem cells
- iPSC
- ESC
- Other stem cells
End-point cell type
- Neural cells (Neurons, Neural Stem/Progenitor Cells, Microglia, Oligodendrocytes, Astrocytes)
- Immune cells (T cells, NK cells, Monocytes/Macrophages )
- Skeletal muscle-like cells
- Cardiomyocytes
- Hepatocytes
- Hematopoietic Progenitor Cell
- Retinal pigment epithelium
- Endothelial Cells
- Photoreceptor cells
- Beta cells
- Chondrocytes
- Osteocytes
- Adipocytes
End-point cell type (organoids)
- Brain organoids
- Liver organoids
- Kidney organoids
- Pancreatic organoids
- Gastric organoids
- Intestinal organoids
- Pulmonary organoids
- Prostate organoids
- Retinal organoids
AcceGen operates an extensive human tissue network and access a diverse range of donors. Stem cells were harvested from screened donors. Following reprogramming, these stem cells were subsequently differentiated into various cells, and play a role in treating graft-versus-host disease (GVHD), multiple sclerosis (MS), Crohn’s disease (CD), amyotrophic lateral sclerosis (ALS), myocardial infarction (MI), and acute respiratory distress syndrome (ARDS), etc.
Workflow
STEP1 Service Consultation
Two-way communication to analyze the project and determine the plan, including the end-point cell type or organoids, the production scale, and desired characterization assays. We will send you a competitive quote.
STEP2 Starting Cells Preparation
The starting cells should be guaranteed negative for bacteria, yeast, fungi, and mycoplasma.
The cell viability should be greater than 80%.
If the starting cell quantity is insufficient, the cells need to be expanded.
If the starting cells are provided by the customer, these cells need to adapt to AcceGen’s culture system to keep homogeneous state before differentiation.
STEP3 Stem Cell Differentiation
Small molecules are used to generate footprint-free end-point cells or organoids.
We can also use our stem cell differentiation expertise to develop a custom differentiation strategy for generating your desired cell or tissue type.
STEP4 Characterization
Antibody staining images and/or flow cytometry data for the cell type-specific markers.
Perform cell viability testing to ensure optimal post-thaw viability.
Optional pathogen testing is available.
Frequently Asked Questions
How much do the stem cell differentiation services cost?
The price for the differentiation services vary based on multiple factors and requirements such as starting stem cells expansion requirement, number of cells required, QC criteria etc. Contact us to share your requirements and start discussion.
What information should I provide to get a quote?
Including but not limited to relevant information of starting cells, end-point cells or organoids, desired quantity of end-point products, specific markers of interest.
How do I ship my starting stem cells?
Dry ice shipment is suggested in the US and liquid nitrogen dry shipper is suggested to ship cryopreserved cells internationally.
What are the deliverables?
- Cryovials of differentiated cells or live culture (in the US) for cells not suitable for cryopreservation.
- Instructions and culture medium for optimal cell maintenance.
- Reports and data.
Get Started Now!
If you have any needs in Stem Cell Differentiation Service, do not hesitate to contact us for free consultation, our dedicated stem cell specialists will provide ongoing support for your studies.
