| Species |
Bovine
|
| Cat.No |
ABC-TC136W
|
| Quality Control |
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
|
| Product Category |
Primary Cells |
| Size/Quantity |
1 vial
|
| Cell Type |
Epithelial Cell
|
| Shipping Info |
Dry Ice
|
| Growth Conditions |
37 °C, 5% CO2
|
| Source Organ |
Rumen Intestine
|
| Disease |
Normal
|
| Biosafety Level |
1
|
| Storage |
Liquid Nitrogen
|
| Product Type |
Rumen Intestinal Cells
|
Description
Primary bovine ruminal epithelial cells (BRECs) are isolated from calf rumen tissue and cultured to retain squamous morphology, tight junctions, desmosomes, and key SCFA transporters (MCT1/MCT4). They actively absorb and metabolize volatile fatty acids, produce ketone bodies, and maintain barrier integrity essential for nutrient uptake and defense. BRECs respond physiologically to insulin, IGF‑1, butyrate, TGF‑β, and pH shifts by modulating proliferation, differentiation, apoptosis, and inflammatory cytokine signaling (e.g., IL‑1β, TNF‑α). These features render BRECs a robust in vitro model for rumen development, acidosis, epithelial transport, immune responses, and dietary or drug effects.
