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Primary Cells

C57BL/6 Mouse Thymus Epithelial Cells

  • For research use only

Cat No.

ABC-TC5502
Product Type

Mouse Primary Cells
Cell Type

Epithelial
Species

C57BL/6 Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Thymus
Disease

Normal
Storage

Liquid Nitrogen

C57BL/6 Mouse Thymus Epithelial Cells support T cell selection, express Foxn1/MHC II,normal diploid karyotype,used in autoimmune, thymic function studies.

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  • C57BL/6 Mouse Thymus Epithelial Cells
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | C57BL/6 Mouse Thymus Epithelial Cells

Description

C57BL/6 Mouse Thymus Epithelial Cells are primary epithelial cells isolated from the thymus tissue of pathogen-free C57BL/6 mice. These cells exhibit polygonal morphology with adherent growth pattern. As a key structural component of the thymic microenvironment, thymus epithelial cells (TECs) support the development and positive/negative selection of T lymphocytes by producing cytokines, chemokines, self-antigens, and extracellular matrix proteins. These cells express key markers like Foxn1 and MHC II, confirming their thymic epithelial identity. They are non-immortalized, retain a normal diploid karyotype, maintaining physiological relevance in vitro. Due to their role in shaping central immune tolerance, these cells are widely used to model autoimmune disorders, thymic involution, and T cell repertoire selection in research. Derived directly from the mouse thymus, these cultures provide a relevant epithelial reference for studies comparing TEC biology with broader mouse epithelium systems.

Product Code

MTECs
Species

C57BL/6 Mouse
Cat.No

ABC-TC5502
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Thymus
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • C57BL/6 mouse primary thymus epithelial cell are a useful model to investigate thymic activities, including hormone secretion and thymocyte development. Thymus epithelial cells also express MHC class II molecules, involved in antigen presentation during immune responses. Considering the tight connection with thymocytes, TECs can be used in the research of immune system, such as identification of modulators in thymocyte development. For example, androgen receptor was identified in the immunohistochemical analysis and hormone-binding assay of thymic epithelial cells. C57BL/6 mouse primary thymus epithelial cells can also be used in some investigations, such as assessing resistance to ionizing radiation.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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