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Immortalized Human Bone Marrow-Derived Mesenchymal Stem Cells

Product Name

Immortalized Human Bone Marrow-Derived Mesenchymal Stem Cells

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1 vial

Biosafety Level


Shipping Info

Dry Ice


Liquid Nitrogen


Human Bone Marrow-derived Mesenchymal Stem Cells (hMSCs) are highly promising for both clinical and experimental applications, owing to their ability to self-renew and differentiate into various mesenchymal lineages. These cells play a critical role in promoting the growth and differentiation of primitive hematopoietic cells, as well as maintaining leukemic cells. However, primary cultures of hMSCs suffer from limitations such as a restricted in vitro lifespan and variable properties among cells from different donors and over time in culture. To overcome these challenges, we have successfully generated immortalized cells by introducing a retrovirus carrying the SV40 large T antigen into primary mesenchymal cells, offering a renewable and consistent source of hMSCs for future therapeutic and research endeavors.


Why Choose Immortalized Human Bone Marrow Derived Mesenchymal Stem Cells from AcceGen?

AcceGen’s Immortalized Human Bone Marrow-Derived Mesenchymal Stem Cells are an ideal choice due to their high viability (>75%), guaranteed sterility without detectable bacteria, fungi, and mycoplasma, and stringent quality control measures. The use of Real-Time PCR to quantify SV40 gene expression ensures the reliability and authenticity of the immortalized cell line, making it a reliable and trustworthy option for research and experimental applications.



Source Organ

Bone Marrow

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).



Immortalized Human Bone Marrow-Derived Mesenchymal Stem Cells (hMSCs) have versatile applications. These cells are valuable for studying the bone marrow microenvironment and understanding the environmental cues that regulate hematopoiesis. Additionally, they find utility in the fields of regenerative medicine, gene therapy, cell differentiation and gene regulation, as well as cell-based screening assays. Immortalized hMSCs serve as essential tools for various research areas with potential implications for therapeutic advancements.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Mesenchymal Stem Cell

Growth Mode


Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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