Home > Products > Immortalized Cell Lines >

Immortalized Human Brain Microvascular Endothelial Cells

Product Name

Immortalized Human Brain Microvascular Endothelial Cells

Price Get Quote
Product Code

IM-HBMEC

Cat.No

ABC-H0025X

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Immortalized Human Brain Microvascular Endothelial Cells (IM-HBMEC) are a specialized cell line developed by immortalizing primary cells using SV40 Large T antigen. These cells have been extensively characterized and demonstrated to maintain the immune barrier properties of primary HBMECs. Flow cytometric analysis comparing IM-HBMEC with primary HBMECs revealed no significant differences in leukocyte migration responses or inflammatory cytokine production. Additionally, IM-HBMECs exhibited similar responses to astrocyte coculture, leukocyte stimulation, and inflammatory cytokine treatment. The immortalized cells showed remarkable longevity, with the ability to undergo more than 30 passages compared to the senescence observed in primary cells after the 3rd passage.

 

Why choose Immortalized Human Brain Microvascular Endothelial Cells from AcceGen?

AcceGen’s Immortalized Human Brain Microvascular Endothelial Cells offer high viability, advanced engineering, stability, sterile conditions, and confirmed absence of viruses (Hepatitis, HPV, Herpes, HIV) and mycoplasma contamination. Trust AcceGen for reliable, safe, and top-quality research.

Disease

Normal

Source Organ

Brain

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

IM-HBMECs offer a cost-effective and practical solution for constructing in vitro models of the blood-brain barrier (BBB). These immortalized cells exhibit exceptional fidelity in terms of barrier resistance, immune migration profiles, and responsiveness to inflammatory cytokines. With their specialized BBB endothelial phenotype, this newly established human cell line provides a readily available in vitro model for studying the properties of the human BBB. IM-HBMECs are particularly valuable for investigating central nervous system infections, offering a valuable alternative to primary brain endothelial cells as a reliable model for studying the blood-brain barrier in such studies.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Endothelial

Growth Mode

Adherent

Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
  • ONLINE INQUIRY
  • PRODUCT REVIEWS
We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time?

Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
Privacy Policy: AcceGen will never sell, rent, or share your personal information with any third parties without your express permission.
Reviews of Immortalized Human Brain Microvascular Endothelial Cells
AcceGen is always trying to do right by our customers and working hard to build a higher quality product.

Your email address will not be published.

AcceGen Scroll Top Button