Home > Products > Primary Cells > Animal Primary Cells > Mouse Primary cells >

C57BL/6 Mouse Type II Alveolar Epithelial Cells

141

Product Name

C57BL/6 Mouse Type II Alveolar Epithelial Cells

Price Get Quote
Cat.No

ABC-H0084X

Species

C57BL/6 Mouse

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

C57BL/6 Mouse Type II Alveolar Epithelial Cells, derived from C57BL/6 mouse lungs, comprise a minor fraction (2-5%) of the lung’s internal surface yet play crucial roles. Responsible for producing, secreting, and recycling pulmonary surfactant, they maintain pulmonary fluid equilibrium by regulating active Na+ transport. Beyond these physiological functions, they function as a frontline defense within the lungs, initiating and modulating immune responses during pulmonary infections or allergies. These cells also display regenerative capabilities, acting as progenitors in the distal lung, capable of repairing the epithelium following injury. Notably, in response to pulmonary vaccinia virus infection, they trigger IFN-β and IFN-stimulated genes through MDA5 and STING-mediated nucleic acid-sensing pathways, contributing to immune responses and feedback loops.

 

Why choose C57BL/6 Mouse Type II Alveolar Epithelial Cells from AcceGen?

C57BL/6 Mouse Type II Alveolar Epithelial Cell from AcceGen is a suitable choice for their superior viability and quality. These cells are meticulously maintained under sterile, optimum incubation conditions, backed by stringent quality control measures to ensure consistent and reliable results in your research endeavors.

Disease

Normal

Source Organ

Alveolar

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

C57BL/6 Type II Mouse Alveolar Epithelial Cells (AECIIs) are essential tools for in vitro investigations into lung diseases like pulmonary fibrosis and lung injury, offering insights into alveolar epithelium regeneration. With high purity and viability, these cells are suitable for genomic, proteomic analyses, and ex vivo culturing to unravel their contributions across biological processes. They are particularly useful in studying how lung AECIIs’ innate immune sensing safeguards against viral infections, enhancing our understanding of defense mechanisms against pathogens.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Mouse Primary Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
  • ONLINE INQUIRY
  • PRODUCT REVIEWS
We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time?

Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
Privacy Policy: AcceGen will never sell, rent, or share your personal information with any third parties without your express permission.
Reviews of C57BL/6 Mouse Type II Alveolar Epithelial Cells
AcceGen is always trying to do right by our customers and working hard to build a higher quality product.

Your email address will not be published.

AcceGen Scroll Top Button