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C57BL/6 Mouse Type II Alveolar Epithelial Cells

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C57BL/6 Mouse Type II Alveolar Epithelial Cells

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C57BL/6 Mouse


1 vial

Biosafety Level


Shipping Info

Dry Ice


Liquid Nitrogen


C57BL/6 Mouse Type II Alveolar Epithelial Cells, derived from C57BL/6 mouse lungs, comprise a minor fraction (2-5%) of the lung’s internal surface yet play crucial roles. Responsible for producing, secreting, and recycling pulmonary surfactant, they maintain pulmonary fluid equilibrium by regulating active Na+ transport. Beyond these physiological functions, they function as a frontline defense within the lungs, initiating and modulating immune responses during pulmonary infections or allergies. These cells also display regenerative capabilities, acting as progenitors in the distal lung, capable of repairing the epithelium following injury. Notably, in response to pulmonary vaccinia virus infection, they trigger IFN-β and IFN-stimulated genes through MDA5 and STING-mediated nucleic acid-sensing pathways, contributing to immune responses and feedback loops.


Why choose C57BL/6 Mouse Type II Alveolar Epithelial Cells from AcceGen?

C57BL/6 Mouse Type II Alveolar Epithelial Cell from AcceGen is a suitable choice for their superior viability and quality. These cells are meticulously maintained under sterile, optimum incubation conditions, backed by stringent quality control measures to ensure consistent and reliable results in your research endeavors.



Source Organ


Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).



C57BL/6 Type II Mouse Alveolar Epithelial Cells (AECIIs) are essential tools for in vitro investigations into lung diseases like pulmonary fibrosis and lung injury, offering insights into alveolar epithelium regeneration. With high purity and viability, these cells are suitable for genomic, proteomic analyses, and ex vivo culturing to unravel their contributions across biological processes. They are particularly useful in studying how lung AECIIs’ innate immune sensing safeguards against viral infections, enhancing our understanding of defense mechanisms against pathogens.

Growth Conditions

37 ℃, 5% CO2

Cell Type


Growth Mode


Product Type

Mouse Primary Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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