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Product Code | GEM 199; GEM199; Goldfish Erythrophoroma-199 |
Species | Gold Fish |
Cat.No | ABC-TC023S |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Erythrophore |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Disease | Erythrophoromas |
Storage | Liquid Nitrogen |
Product Type | Gold Fish Red Pigment Cells |
The GEM-199 is a tumor cell line derived from an erythrophoroma of goldfish (Carassius auratus) red pigment cell. GEM-199 adherent culture properties. The research demonstrated that GEM-199 has a greater resistance to γ-rays compared to mammalian cells and CAF-MM1 cells, which were derived from the normal fin tissue of goldfish. The photoreactivation following UV irradiation was observed in GEM-199 cells, impacting both survival and mutation rates. Therefore, these cells can be used to investigate the lethal and mutational effects of various radiations.
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The GEM-199 cell line serves as a vital tool in understanding the biology of erythrophoroma, particularly its invasive properties. Additionally, researchers harness its capabilities to explore the radiosensitivity and lethal impact of gamma-rays on cellular structures. This versatile cell line not only enables investigations into DNA damage and repair mechanisms but also aids in unraveling the complexities of tumor invasion and response to radiation, fostering advancements in cancer research and therapeutic strategies.