Tumor Cell Lines

HGC-27

  • For research use only

Cat No.

ABC-TC0384

Product Type

Human Gastric Cancer Cell Lines

Cell Type

Epithelial

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lymph Node

Disease

Gastric Cancer

Product Code

HGC 27; HGC27

HGC-27 Cell Line is a gastric cancer cell model used for studying tumor progression, drug resistance, and novel therapeutic targets in oncology research.

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Description

HGC-27 is a human gastric adenocarcinoma cell line derived in 1975 from the metastatic lymph node of a 37-year-old male patient with poorly differentiated gastric adenocarcinoma. These cells exhibit epithelial-like morphology and adhere firmly in culture. They display a rapid doubling time of approximately 17 hours. Chromosomal analysis reveals aneuploid chromosomal instability with a modal chromosome number ranging from 109 to 110. This cell line demonstrates strong tumorigenic potential in xenograft models and is known for its robust engraftment efficiency in preclinical studies. HGC-27 secretes mucins, making it a valuable model for investigating mucin-related pathobiology. It is widely used to investigate gastric cancer progression, cell proliferation, migration, invasion, and cancer stem-like properties.

Product Code

HGC 27; HGC27

Species

Human

Cat.No

ABC-TC0384

Product Category

Tumor Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lymph Node

Disease

Gastric Cancer

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Gastric Cancer Cell Lines

Application

  • HGC-27 cells are extensively used in human gastric cancer research to study critical cellular processes such as proliferation, migration, and invasion. Their aggressive phenotype and mucin-secreting properties make them an ideal platform for evaluating anticancer drugs and understanding the molecular mechanisms driving tumor progression. This cell line provides a versatile and clinically relevant model for preclinical drug screening and the development of targeted therapies for gastric cancer, ultimately supporting efforts to identify potential therapeutic strategies against this aggressive malignancy.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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