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NUGC-4 |
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| Product Name |
NUGC-4 |
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| Price | Get Quote | |||
| Product Code | NUGC4; NU-GC-4; Nagoya University-Gastric Cancer-4 |
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| Cat.No |
ABC-TC0862 |
Species |
Human |
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| Size/Quantity |
1 vial |
Biosafety Level |
1 |
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| Shipping Info |
Dry Ice |
Storage |
Liquid Nitrogen |
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| Description |
NUGC-4, also referred to as ‘Nagoya University-Gastric Cancer-4’, ‘NU-GC-4’, and ‘NUGC4’, is a human gastric cancer cell line established from the patient during surgery. This cell line was derived from signet ring cell carcinoma of human stomach at the metastatic paragastric lymph nodes. When cultured in vitro, NUGC-4 cells
Why choose NUGC-4 from AcceGen? AcceGen supports NUGC-4 cells at more than 5×105 cells in 1mL volume with professional packaging of cryopreservation to ensure high quality and viability. Accegen NUGC-4 is negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. With the condition provided by AcceGen, the population doubling of NUGC-4 can reach more than 15 times. |
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| Source Organ | Lymph Node |
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| Recommended Medium And Supplement | RPMI 1640 + 10% FBS |
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| Citation Guide |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). |
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| Application | FOR RESEARCH USE ONLY As a cancer cell line, NUGC-4 is widely used in scientific research, such as searching for key factors of the formation of human gastric cancer and targets for anti-cancer drugs. Epidermal growth factor (EGF) strongly activates the tyrosine phosphorylation in NUGC-4. Phosphatidylinositol 3-kinase (PI 3-kinase), which is mainly activated by tyrosine kinases, was precipitated with anti-phosphotyrosine antibodies in NUGC-4. Exogenous hepatocyte growth factor can stimulate the proliferation of NUGC-4, and MET tyrosine kinase inhibitors inhibited this proliferation of NUGC-4. Investigation of NUGC-4 cell line and the interactions with growth factors may provide the direction for identifying the signaling pathway of gastric cancer and screening of potential therapeutic targets. |
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| Growth Conditions | 37 ℃, 5% CO2 |
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| Product Type |
Human Gastric Cancer Cell Lines |
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| Product Image |
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exhibit a spherical epithelial-like morphology and display characteristics of cell adhension, although a few free-floating cells may be also present. On average, the doubling time of NUGC-4 is about 30 hours, and it should be cultured in PRMI1640 with 10% FBS.- ONLINE INQUIRY
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