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HighQC™ CHD8+/+ Induced Pluripotent Stem Cell

Product Name

HighQC™ CHD8+/+ Induced Pluripotent Stem Cell

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Cat.No

ABC-SC0124T

Species

Human

Size/Quantity

1 vial

Biosafety Level

2

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

CHD8 has a role in chromatin dynamics, transcription and cell survival in which it interacts with p53 to regulate cell cycle genes. It has been associated with developmental disorders like ASD (autism spectrum disorders). CHD8+/+ induced pluripotent stem cells (iPSC) were derived from skin fibroblasts obtained from a typically developing male control who had a normal karyotype. The line is the isogenic control used to generate T2500, in which a CHD8 allele was knocked out using CRISPR/Cas9 gene editing. The two lines can be utilized by researchers interested in brain development, neurodevelopmental disorders, and cancer.

Source Organ

Human Stem Cell Collection

Citation Guide

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Product Type

Human Induced Pluripotent Stem Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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