Home > Products > Mesenchymal Stem Cells (MSC) >
HighQC™ Human Mesenchymal Stem Cell-Expressing OCT3/4 | ||||
---|---|---|---|---|
Product Name | HighQC™ Human Mesenchymal Stem Cell-Expressing OCT3/4 | |||
Price | Get Quote | |||
Cat.No | ABC-SC0032T | Species | Human | |
Size/Quantity | 1 vial | |||
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | It is well-established that induced pluripotent stem cells may be generated by co-transfection of four genes: Oct3/4, Sox2, Kfl4 and c-Myc, into somatic adult cells resulting in re-programming of these cells to pluripotency equivalent to that of embryonic stem cells. It has recently been shown by independent research including results from our laboratory that over-expression of a single gene, Oct3/4, in adult neural or mesenchymal stem cells also results in enhanced differentiation capacity including pluripotency. This development simplifies iPS generation and may reflect levels of endogenous expression of Sox2, Kfl4 and c-Myc in adult stem cells that are multipotent. Also, since the Oct3/4 promoter has well-known response elements and transcription control mechanisms, re-programming based on environmental cues is now feasible through use of small molecular agents that selectively activate expression of Oct3/4. Our human MSCs expressing Oct3/4 allow further investigation of iPSC mechanisms. Optimizing your hMSC Cultures: | |||
Disease | Normal | |||
Recommended Medium And Supplement | ABM-SM0032T HighQC™ Human Mesenchymal Stem Cell-Expressing OCT3/4 Medium Kit | |||
Citation Guide | When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | For research use only | |||
Growth Conditions | 37 ℃, 5% CO2 | |||
Cell Type | Mesenchymal Stem Cell | |||
Growth Mode | Adherent | |||
Product Type | Human Mesenchymal Stem Cells | |||
Product Image |
- ONLINE INQUIRY
- PRODUCT REVIEWS
Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.