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HighQC™ SACK-Xs Lig-8 Clonal Adult Rat Hepatocytic Stem Cell

Product Name

HighQC™ SACK-Xs Lig-8 Clonal Adult Rat Hepatocytic Stem Cell

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Cat.No

ABC-SC0108T

Species

Rat

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Growing and expanding primary, differentiated adult cells in culture is difficult and laborious because many differentiated cells can only be maintained in vitro for a limited period of time. However, for controlled experiments, it may be necessary to maintain a consistent population of cells.

Maintaining a population of adult stem cells (ASCs), allows one to exponentially propagate a population of cells in vitro, and induce differentiation when desired. This is possible with SACK cell strains and specified cell culture conditions.

SACK ASC cell properties – Long-term propagation in xanthosine (Xs)-supplemented medium

Suppressed asymmetric cell kinetics
Differentiated progeny cell properties – Xs-free medium, confluent monolayer, serum reduction

Hepatocyte Properties

Albumin secretionAlpha-fetoprotein secretion (indicates presence of hepatoblasts)Alpha 1-antitrypsin expressionH4 hepatocyte antigen expressionInducible cytochrome P450 activity (CYP1A1, CYP1A2) Constitutive cytochrome P450 metabolism (CYP2E1)Spheroid formationBinucleation
Biliary Properties

CK7 expression (biliary epithelial cell marker)

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Cell Type

Stem Cell

Growth Mode

Adherent

Product Type

Animal Adult Stem Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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