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HighQC™ SACK-Xs Lig-8 Clonal Adult Rat Hepatocytic Stem Cell

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HighQC™ SACK-Xs Lig-8 Clonal Adult Rat Hepatocytic Stem Cell

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1 vial

Biosafety Level


Shipping Info

Dry Ice


Liquid Nitrogen


Growing and expanding primary, differentiated adult cells in culture is difficult and laborious because many differentiated cells can only be maintained in vitro for a limited period of time. However, for controlled experiments, it may be necessary to maintain a consistent population of cells.

Maintaining a population of adult stem cells (ASCs), allows one to exponentially propagate a population of cells in vitro, and induce differentiation when desired. This is possible with SACK cell strains and specified cell culture conditions.

SACK ASC cell properties – Long-term propagation in xanthosine (Xs)-supplemented medium

Suppressed asymmetric cell kinetics
Differentiated progeny cell properties – Xs-free medium, confluent monolayer, serum reduction

Hepatocyte Properties

Albumin secretionAlpha-fetoprotein secretion (indicates presence of hepatoblasts)Alpha 1-antitrypsin expressionH4 hepatocyte antigen expressionInducible cytochrome P450 activity (CYP1A1, CYP1A2) Constitutive cytochrome P450 metabolism (CYP2E1)Spheroid formationBinucleation
Biliary Properties

CK7 expression (biliary epithelial cell marker)

Source Organ

Animals Stem Cell Collection

Citation Guide

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For research use only

Product Type

Animal Adult Stem Cells

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