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huH-1

Product Name

huH-1

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Product Code

huH-1; HUH-1; huH 1; HuH1; HUh1; HUH1; huH1

Cat.No

ABC-TC0434

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The huH-1 is a human hepatocellular carcinoma (HCC) cell line derived from the liver tissue of a patient with adult hepatocellular carcinoma. Hepatitis B virus (HBV) is detected in the huH-1 cell line with a high transcriptional activity, and hepatitis B surface antigen (HBsAg) can be produced by huH-1. The huH-1 presents the typical characteristics of epithelial morphology and expresses several biomarkers of epithelial-mesenchymal transition, such as E-cadherin, ZO-1, N-cadherin, Vimentin, Snail, and Slug. Otherwise, the chromosomal translocation is also identified in huH-1; an integration event occurs between chromosome 9 and 20 with a fusion of 1100bp HBV DNA.

 

Why choose huH-1 from AcceGen?

AcceGen provides huH-1 cell line with high standards of sterility, being negative for bacterial, fungal, and mycoplasma, to ensure the safety and integrity of the product. The huH-1 cell line is supported by excellent production and cryopreservation methods, ensuring high viability and maximum growth performance.

Disease

Hepatocellular Cancer

Source Organ

Liver

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

For many years, huH-1 has been widely employed as a valuable research tool to investigate HBV and its association with carcinogenesis. HCC is a high-risk malignant tumor, and its 5-year survival rate is below 50%. The precise understanding of the pathogenesis of HCC remains incomplete. huH-1 can be used to study the pathogenesis of HCC and screen for effective diagnostic markers and therapeutic targets.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial-like

Product Type

Human Liver Cancer Cell Lines

Product Image

AcceGen Frozen Cells & Cell Lines

AcceGen product mpp-89 cell line

Related Resources

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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