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huH-1 |
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Product Name |
huH-1 |
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Price | Get Quote | |||
Product Code | huH-1; HUH-1; huH 1; HuH1; HUh1; HUH1; huH1 |
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Cat.No |
ABC-TC0434 |
Species |
Human |
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Size/Quantity |
1 vial |
Biosafety Level |
1 |
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Shipping Info |
Dry Ice |
Storage |
Liquid Nitrogen |
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Description |
The huH-1 is a human hepatocellular carcinoma (HCC) cell line derived from the liver tissue of a patient with adult hepatocellular carcinoma. Hepatitis B virus (HBV) is detected in the huH-1 cell line with a high transcriptional activity, and hepatitis B surface antigen (HBsAg) can be produced by huH-1. The huH-1 presents the typical characteristics of epithelial morphology and expresses several biomarkers of epithelial-mesenchymal transition, such as E-cadherin, ZO-1, N-cadherin, Vimentin, Snail, and Slug. Otherwise, the chromosomal translocation is also identified in huH-1; an integration event occurs between chromosome 9 and 20 with a fusion of 1100bp HBV DNA.
Why choose huH-1 from AcceGen? AcceGen provides huH-1 cell line with high standards of sterility, being negative for bacterial, fungal, and mycoplasma, to ensure the safety and integrity of the product. The huH-1 cell line is supported by excellent production and cryopreservation methods, ensuring high viability and maximum growth performance. |
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Disease | Hepatocellular Cancer |
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Source Organ | Liver |
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Recommended Medium And Supplement | DMEM + 10% FBS |
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Citation Guide |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). |
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Application | FOR RESEARCH USE ONLY For many years, huH-1 has been widely employed as a valuable research tool to investigate HBV and its association with carcinogenesis. HCC is a high-risk malignant tumor, and its 5-year survival rate is below 50%. The precise understanding of the pathogenesis of HCC remains incomplete. huH-1 can be used to study the pathogenesis of HCC and screen for effective diagnostic markers and therapeutic targets. |
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Growth Conditions | 37 ℃, 5% CO2 |
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Cell Type | Epithelial-like |
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Product Type |
Human Liver Cancer Cell Lines |
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