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Hep 3B

Product Name

Hep 3B

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Product Code

Hep 3B2_1-7; HEP3B217; Hep 3B2; HEP-3B2; HEP3B2; Hep-3B; HEP-3B; Hep 3B; Hep3B; HEP3B

Cat.No

ABC-TC5585

Species

Human

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Hep 3B is a human hepatoma cell line originally derived from liver tissue obtained from an 8-year-old Black patient with liver cancer. These cells harbor an integrated hepatitis B virus genome and display an epithelial morphology. Notably, Hep3B cells possess tumorigenic properties in nude mice. Chromosomally, they maintain an average of 60 chromosomes per cell, with a predominant subtetraploid mode of 82. In terms of gene expression, this cell line exhibits the production of various proteins including alpha-fetoprotein (AFP), hepatitis B surface antigen (HBsAg), albumin, alpha-2-macroglobulin, alpha-1-antitrypsin, transferrin, alpha-1-antichymotrypsin, haptoglobin, ceruloplasmin, plasminogen complement (C3, C4), C3 activator, fibrinogen, alpha-1 acid glycoprotein, alpha-2-HS-glycoprotein, beta-lipoprotein, and retinol-binding protein.

 

Why choose Hep 3B from AcceGen?

Hep 3B cells from AcceGen offer exceptional viability and quality, cultivated under expert care in optimal conditions, ensuring sterility by being free of bacteria, fungi, and mycoplasma. Their identity is confirmed through STR analysis, and they are detected to express HBV, making them a reliable choice for various research applications.

Disease

Hepatocellular Cancer

Source Organ

Liver

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The Hep 3B cell line serves as a vital tool in biomedical research, particularly in elucidating the intricate relationship between HBV infection and the development of hepatocellular carcinoma. Additionally, these cells find widespread utility in drug metabolism and hepatotoxicity studies, offering insights into the effects of various compounds on the liver. Furthermore, Hep3B cells are valuable for investigating plasma protein biosynthesis and studying the interplay between the hepatitis B virus genome and tumorigenicity, making them indispensable for a range of experimental models and scientific inquiries.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Human Liver Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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