Human Hepatocytes (HH) are hepatic cells isolated from the whole human liver, making up 80% of the liver’s mass. Liver hepatocytes are multifunctional. Hepatocyte involves in the production and synthesis of functional proteins that participate in energy metabolism, biotransformation, detoxification, etc. Hepatocytes secrete many materials including structural protein and intracellular enzymes, cholesterol, bile, detoxify substances. Understanding the molecular mechanisms of the liver is beneficial to elucidate new therapies for treatment of hepatic disease.
Primary hepatocyte cultures are unable to expand, which is challenging for long-term research on understanding the regulation of human hepatocytes.
Why Choose Human Hepatocytes from AcceGen?
AcceGen cryopreserves our Human Hepatocytes for about 1 x 10^6 cells/mL, characterized by immunofluorescence with specific antibodies against albumin, cytokeratin-18 and vimentin.
Expanding or long-term culturing is not recommended, as the cells do not proliferate in culture.
Immortalized Human Hepatocytes are also available in AcceGen.
All cells test negative for mycoplasma, bacteria, yeast, and fungi.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only
Applications of Human Hepatocytes
Constitute a more predictive model for pharmaceutical research
Drug metabolism study, including clearance, hepatotoxicity, drug-drug interactions
CYP enzymes expression or inhibition studies
-Backed by AcceGen advanced technology
-Ship cryopreserved cells in dry ice
-Quality-tested for accurate results
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