Human Kupffer Cells

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Human Kupffer Cells
Product Name	Human Kupffer Cells
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Cat.No	ABC-TC4369	Species	Human
Size/Quantity	1 vial
Shipping Info	Dry Ice	Storage	Liquid Nitrogen
Description	Isolated and enriched from dissociated human liver tissue, Human Kupffer cells (HKC) are the resident macrophages in human liver. Kupffer cells are the densest innate liver immune cells and the first line of defense against bacteria and toxins in the intestine. Liver Kupffer cells have typical macrophages abilities like modulating hepatic inflammation and injury. Activated hepatic Kupffer cells could release inflammatory cytokines, growth factors and reactive oxygen species. In vivo, the activation of Kupffer cells could mediate inflammation that develop into liver diseases such as Non-Alcoholic Fatty Liver Disease (NAFLD), Non-Alcoholic Steatohepatitis (NASH), and liver damage associated with certain bioactivated chemicals. Why Choose Human Kupffer Cells from AcceGen? AcceGen cryopreserves our Human Kupffer Cells for about 5 x 10^5 cells/vial after isolation, without being cultured.
Quality Control	All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Citation Guide	When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Application	For research use only Kupffer Cells Applications Co-culturing with other cells to mimic lacking in vitro models for analyzing immune-mediated drug-induced hepatotoxicity In vitro drug metabolism and pharmacokinetics (DMPK) assays Investigation of cytokine releases that response to inflammation Chronic liver injury research Human Kupffer Cells are proved to be inducible with lipopolysaccharide (LPS) with the evaluation. Human Kupffer Cells also keep high activation potential.
Key Features	Backed by AcceGen advanced technology Ship cryopreserved cells in dry ice Quality-tested for accurate results
Product Type	Hepatic Cells
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