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Primary Cells

Human Hepatic Progenitor Cells

  • For research use only

Cat No.

ABC-TC3643
Product Type

Hepatic Cells
Cell Type

Progenitor Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

Liquid Nitrogen

Human Hepatic Progenitor Cells support studies of liver regeneration, fibrosis progression, and hepatocyte differentiation in hepatic biology applications.

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  • Human Hepatic Progenitor Cells
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Hepatic Progenitor Cells

Description

Human Hepatic Progenitor Cells (HPCs) are bipotential epithelial progenitor cells isolated from healthy adult human liver tissue, associated with the canals of Hering and periportal regions in vivo. These small oval cells exhibit a large nucleus with scant cytoplasm and express progenitor markers such as EpCAM, OV6, KRT7, KRT19, AFP, CD90, and CD117. HPCs can be either adherent or in suspension and are suitable for regenerative, drug metabolism, toxicity, and systems biology assays.Their robust proliferative potential, clinically relevant marker profile, and lineage plasticity make HPCs a powerful tool for liver disease modeling and translational research. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Hepatic Progenitor Cells, Liver Progenitor Cells Human, HPCs, Human Hepatic Stem Cells, Oval Cells Human
Species

Human
Cat.No

ABC-TC3643
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Progenitor Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Hepatic Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HPCs serve as valuable models for liver regeneration, ductular reaction analysis, and hepatocarcinogenesis studies by enabling differentiation into hepatocytes and cholangiocytes under modulation of Notch, Wnt/β-catenin, and other pathways. They are excellent tools for assessing drug metabolism, toxicology, and safety screening, given their hepatic lineage functions. These cells are also used in disease modeling of chronic liver injury, fibrosis, and hepatic cancer stem cell behavior, and as potential candidates for cell-based therapeutic strategies.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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To support a consistent result
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