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Primary Cells

Human Pooled Hepatocytes(Heps 10)

  • For research use only

Cat No.

ABC-TC3458
Product Type

Hepatic Cells
Cell Type

Hepatocyte
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Storage

Liquid Nitrogen

Human Pooled Primary Hepatocytes (Heps) provide an ideal culture model for drug testing and drug development.

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  • Human Pooled Hepatocytes(Heps 10)
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Pooled Hepatocytes(Heps 10)

Description

Human Pooled Hepatocytes (Heps 10) are a primary cell population formed by mixing hepatocytes from 10 different donors. Morphologically, these cells exhibit typical characteristics of hepatic parenchymal cells, featuring a polygonal outline and binucleated structure, and form a confluent monolayer after adherence. In terms of molecular markers, they contain cytochrome P450 enzymes (such as CYP3A4 and CYP2C9), bile acid metabolism-related enzymes (e.g., UGT1A1 and SULT2A1), as well as proteins like albumin (ALB). Functionally, they are involved in several key hepatic physiological processes and respond to hepatocyte growth factors that regulate proliferation and metabolic activity, making them widely used in cell-based liver assays for drug metabolism and toxicity evaluation. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Human Pooled Hepatocytes Heps10, Human Hepatocytes Pool of 10 Donors, Pooled Primary Human Hepatocytes 10, Heps 10, Human Liver Cells Pooled 10
Species

Human
Cat.No

ABC-TC3458
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Hepatocyte
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Liver
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Hepatic Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Pooled Hepatocytes (Heps 10) can be used to study specific metabolic pathways of drugs in vitro. With metabolic enzymes such as the cytochrome P450 system, they can predict drug metabolites and metabolic rates. They are also suitable for evaluating potential hepatotoxicity by monitoring changes in cell morphology and related enzyme activity.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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