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Home > Products > Blood System Primary Cells >

Human Cardiac Fibroblasts

Product Name

Human Cardiac Fibroblasts

Price Get Quote
Product Code

HCF

Cat.No

ABC-TC3533

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human Cardiac Fibroblasts (HCFs) are isolated from heart tissue, providing structural support for cardiac myocytes. HCF is one of the major cellular components in the heart, participating in heart function, homeostasis, and structure. Cardiac fibroblast cells secrete collagen and play a role in providing structural support for the heart. The cardiac fibroblast cell proliferation and synthesis of matrix are vital to scar formation in myocardial infarction and cardiac fibrosis. However, inappropriate cardiac fibroblast proliferation is a causative factor in cardiac fibrosis.
After heart injury, some chemical signals like growth factors, cytokines, and matrikines are secreted in paracrine or autocrine manner. Those factors act on cardiac fibroblasts via changing fibroblast gene expression and boosting cell migration to the injured area, which then promote wound healing and scar formation.
 
Why Choose HCF from AcceGen?
HCFs are in low passage for the best viability and plating efficiency and able to passage 15 passages under instructions.
Cardiac fibroblast cells are characterized by immunofluorescence with antibody specific to fibronectin.
Fibroblast specific media is optimized for HCF characteristics. Optimized Xeno-free media culturing cardiac fibroblast can be used to establish the model for would healing and other basic cell biology study. Optimized Xeno-free media are also available in AcceGen.

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Cardiac fibroblast culture has been widely applied in studying the remodeling of the cardiac matrix by physiological (exercise) and pathological (hypertension) stressors. Cardiac fibroblast model is excellent to study extracellular matrix producing and remodeling, as well as myocardial responses to injury like wounds, toxicology and pathology. Suitable to establish serum-free human feeder layers for human embryonic stem cell cultures.

Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Product Type

Cardiac Cells

Product Image AcceGen Frozen Cells & Cell Lines
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