Human Choroid Plexus Epithelial Cells

In central nervous system, the choroid plexus acts as a barrier that separates the blood from cerebrospinal fluid (CSF). It is composed of cuboidal epithelium surrounding capillaries that embedded in a loose connective tissue. The choroid plexus epithelial cells (CPECs), linked by tight junctions, form a neuroprotective barrier by regulating the exchange of electrocytes, nutrients, metabolic wastes, and xenobiotics into and out of the central nervous system. The choroid plexus epithelium is responsible for synthesis and secretion of CSF, regulation of hormone signaling and passage of leukocytes during brain injury and infections. Morphological changes such as atrophy of choroidal epithelial cells, are commonly seen in aging and neurological disorders such as Alzheimer disease.
Why choose Human Choroid Plexus Epithelial Cells from AcceGen?
Human choroid plexus epithelial cells are derived from human choroid plexus. Cells are cryopreserved immediately after purification and delivered in dry ice. Each vial contains > 5×10^5 cells in 1 ml volume. Choroidal epithelial cells are characterized with antibodies specific to cytokeratin-18, -19 and vimentin. Cells are tested negative for HIV-1, HBV, HCV and other pathogens. Human choroid plexus epithelial cells are quality tested and guaranteed to further expand for 5 population doublings when cultured in AcceGen recommended cell culture media.