Home > Products > Human Primary Cells >

Human Dendritic Cells

Product Name

Human Dendritic Cells

Price Get Quote
Cat.No

ABC-TC3973

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human dendritic cells (DC) are specialized antigen-presenting cells that play a crucial role in initiating and regulating immune responses. They have the unique ability to activate naïve T cells and promote their differentiation into effector cells. Additionally, they are involved in maintaining immune tolerance under normal physiological conditions. Human DCs can be distinguished by their high expression of major histocompatibility complex class II molecules (MHC-II) and CD11c. To ensure detailed characterization, these cells are tested for specific surface markers, including CD11c+, CD86+, CD80+, HLADR+, and CD14. In culture, human DCs can survive for up to 7 days as immature dendritic cells (iDCs) when exposed to appropriate cytokines like IL-4 and GM-CSF. Moreover, these cells can be differentiated into mature dendritic cells by the addition of TNF-α and IL-1β.

 

Why choose Human Dendritic Cells from AcceGen?

Choosing human dendritic cells from AcceGen offers several advantages. Our cryopreserved human dendritic cells guarantee a high cell count of ≥3 million viable cells per ampoule. The expression levels of key markers such as CD80, CD86, HLA-DR, CD11c, and CD14 are tested. Importantly, the cells are screened for the absence of HIV-1, hepatitis B, and hepatitis C in all donors and/or cell lots. A Certificate of Analysis can be provided for each purchased cell lot, ensuring quality and traceability.

Disease

Normal

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Human dendritic cells (DCs) have diverse applications in various fields. They are crucial for antigen presentation and uptake, enabling the activation and differentiation of T cells. In primary research, DCs are extensively studied to understand their role in immunology and pharmacology, particularly in drug-induced immunosuppression of cytokine secretion. Additionally, there is a growing interest in harnessing the potential of human DCs in clinical settings, particularly in antitumor immunity, where they can be investigated for their effectiveness as a potential therapeutic approach.

Growth Conditions

37 ℃, 5% CO2

Cell Type

DC Cell

Product Type

Nervous Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
  • ONLINE INQUIRY
  • PRODUCT REVIEWS
We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time?

Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
Privacy Policy: AcceGen will never sell, rent, or share your personal information with any third parties without your express permission.
Reviews of Human Dendritic Cells
AcceGen is always trying to do right by our customers and working hard to build a higher quality product.

Your email address will not be published.

AcceGen Scroll Top Button
Copy link
Powered by Social Snap