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Immortalized Mouse Schwann Cell Line

Product Name

Immortalized Mouse Schwann Cell Line

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Cat.No

ABI-TC133D

Species

Mouse

Size/Quantity

1 vial

Biosafety Level

2

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Schwann cells are valuable tools for diabetic neuropathy pathogenesis involving glycation, reduced regenerative capability, oxidative stress, and other neurodegenerative diseases. The Immortalised Mouse Schwann Cells express glial cell markers (S100, GFAP, p75NTR); transcription factors involved in Schwann cell development and peripheral myelin formation (Krox20, Oct6, PAX3, and SOX10); and neurotrophic factors (NGF, BDNF, GDNF, and CNTF). In the presence of growth factors, such as PDGF-BB, aFGF, bFGF, or TGF-β1, these cells exhibit mitogenic reponses. The Immortalized Mouse Schwann Cell Line may be used to study action mechanisms involved in peripheral nerve regeneration, and as an in vitro model to assess the pathogenesis of neurological diseases.

Disease

Normal

Source Organ

Brain

Quality Control

Immunoreactivity to cell markers

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Morphology

Spindle shaped

Immortalization Method

Spontaneous Immortalization

Growth Conditions

37 ℃, 5% CO2

Cell Type

Schwann Cell

Growth Mode

Adherent

Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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