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Immortalized Mouse Schwann Cell Line

Product Name

Immortalized Mouse Schwann Cell Line

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1 vial

Biosafety Level


Shipping Info

Dry Ice


Liquid Nitrogen


Schwann cells are valuable tools for diabetic neuropathy pathogenesis involving glycation, reduced regenerative capability, oxidative stress, and other neurodegenerative diseases. The Immortalised Mouse Schwann Cells express glial cell markers (S100, GFAP, p75NTR); transcription factors involved in Schwann cell development and peripheral myelin formation (Krox20, Oct6, PAX3, and SOX10); and neurotrophic factors (NGF, BDNF, GDNF, and CNTF). In the presence of growth factors, such as PDGF-BB, aFGF, bFGF, or TGF-β1, these cells exhibit mitogenic reponses. The Immortalized Mouse Schwann Cell Line may be used to study action mechanisms involved in peripheral nerve regeneration, and as an in vitro model to assess the pathogenesis of neurological diseases.

Quality Control

Immunoreactivity to cell markers

Growth Properties


Citation Guide

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For research use only


Spindle shaped

Immortalization Method

Spontaneous Immortalization

Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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