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Primary Cells

Human Gastric Epithelial Cells

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Human Stomach Epithelial Cells are isolated from normal human stomach tissue. Cells are cryopreserved at passage 3 and delivered frozen.
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Gastric Epithelial Cells
Species

Human
Cat.No

ABC-HP021X
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Gastric
Disease

Normal
Storage

Liquid Nitrogen
Product Type

Gastric Cells
Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Description

Human Gastric Epithelial Cells are isolated from human gastric epithelial tissue. Morphologically, these cells are arranged in polygonal or cobblestone-like patterns. They maintain the gastric mucosal barrier, protecting the stomach wall from erosion by gastric acid and digestive enzymes.They are able to secrete mucus such as the gastric secretory mucin MUC5AC. In vitro studies have shown that primary gastric epithelial cells cultured in the presence of retinol can synthesize retinoic acid (RA) [1-2]. They also express key gastric epithelial markers such as TFF1, CDX2, and MUC6, which are involved in mucosal protection and gastric epithelial identity.Recent studies have revealed their capacity to secrete various antimicrobial peptides and chemokines that contribute to gastric innate immunity and Helicobacter pylori defense.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

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Application

  • Human Gastric Epithelial Cells can be used to explore the pathogenesis of gastritis, gastric ulcer and gastric cancer, especially the host cell response to Helicobacter pylori infection. It can also be used to evaluate the efficacy and toxicity of antacids, gastric mucosal protectants and chemotherapy drugs, providing a basis for personalized treatment.

Frequently Asked Questions

  • What are Human Gastric Epithelial Cells?

    Human Gastric Epithelial Cells are cells that line the surface of the stomach. They play a crucial role in secreting gastric acid, enzymes, and mucus, as well as forming a protective barrier against the harsh acidic environment of the stomach.

  • What functions do Human Gastric Epithelial Cells perform in the stomach?

    Human Gastric Epithelial Cells are responsible for secreting hydrochloric acid and digestive enzymes, producing mucus to protect the stomach lining from acid and mechanical damage, and absorbing some nutrients. They also contribute to the stomach’s barrier function, preventing pathogens from entering the body.

  • What are Human Gastric Epithelial Cells used for in research?

    Human Gastric Epithelial Cells are used in research to study gastric diseases such as gastric ulcers, gastritis, and gastric cancer. They are also utilized to investigate the effects of various drugs on the stomach lining, understand Helicobacter pylori infection mechanisms, and develop treatments for gastric disorders.

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