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Primary Cells

Human Gastric Smooth Muscle Cells

  • For research use only

Cat No.

ABC-TC3626
Product Type

Gastric Cells
Cell Type

Smooth Muscle Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Gastric
Disease

Normal
Storage

Liquid Nitrogen

Human Gastric Smooth Muscle Cells from AcceGen Research Laboratories are isolated from the human stomach.

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  • Human Gastric Smooth Muscle Cells
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Gastric Smooth Muscle Cells

Description

Human Gastric Smooth Muscle Cells (HGSMC) are adherent, spindle-shaped contractile cells isolated from healthy adult human stomach tissue. As visceral smooth muscle in the gastric wall, they express α-smooth muscle actin and desmin. HGSMC mediate gastric motility through intracellular Ca²⁺ signaling, G-protein activation, PKCε pathways, and voltage-dependent sodium currents, while also expressing endothelin (ET) and endothelial nitric oxide synthase (eNOS), which contribute to plateau potential generation. Their morphology, marker profile, and electrophysiological traits make them ideally suited for gastric motility and smooth muscle research. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Gastric Smooth Muscle Cells, Stomach SMCs Human, HGSMCs, Gastric Muscularis Cells, Human Stomach Smooth Muscle Cells
Species

Human
Cat.No

ABC-TC3626
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Smooth Muscle Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Gastric
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Gastric Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HGSMC provide a robust in vitro model for investigating gastric contractility, electrophysiology, and signal transduction mechanisms involving Ca²⁺, sodium currents, ET, and eNOS pathways. They are widely used in studies of gastrointestinal motility disorders such as gastroparesis and functional dyspepsia, enabling screening of smooth muscle-modulating drugs, ion channel regulators, and contractility modifiers. These cells also support tissue engineering and co-culture systems aimed at understanding gastric physiology and drug responses.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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