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Primary Cells

Human Small Airway Epithelial Cells

  • For research use only

Cat No.

ABC-TC3811
Product Type

Tracheal Cells
Cell Type

Epithelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Small Airway
Disease

Normal
Storage

Liquid Nitrogen

The small airways are located at the interface between alveoli and conducting airways.

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  • Human Small Airway Epithelial Cells
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Home | Primary Cells | Human Primary Cells | Respiratory System Primary Cells | Human Small Airway Epithelial Cells

Description

Human Small Airway Epithelial Cells (hSAECs) are primary cells isolated from the epithelial lining of distal bronchioles (less than 2 mm in diameter) in healthy human lung tissue. These adherent, polygonal cells display a cobblestone morphology and are cryopreserved at early passage to preserve their differentiation capacity. hSAECs express key airway epithelial markers including cytokeratin-18 (CK18), E-cadherin, MUC1, and surfactant proteins such as SP-A, and are capable of mucociliary differentiation under air-liquid interface (ALI) culture. They respond to cytokines, pollutants, and pathogens, making them ideal for respiratory disease modeling. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Human Small Airway Epithelial Cells, SAECs, Small Bronchial Epithelial Cells, Distal Airway Epithelial Cells
Species

Human
Cat.No

ABC-TC3811
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Small Airway
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Tracheal Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Small Airway Epithelial Cells (hSAECs) are essential for studying small airway remodeling, mucociliary clearance, and inflammatory responses in diseases such as chronic obstructive pulmonary disease (COPD), asthma, and bronchiolitis obliterans. These human airway epithelial cells support toxicology studies and viral infection modeling such as RSV and influenza, and inhalation drug delivery research. Under ALI conditions, they differentiate into goblet, ciliated, and basal-like cells, enabling physiologically relevant airway models.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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