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MDA-MB-453 | ||||
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Product Name | MDA-MB-453 | |||
Price | Get Quote | |||
Product Code | MDA-MB 453; MDA MB 453; MDA-MB453; MDAMB453; MDA-453; MDA453; MD Anderson-Metastatic Breast-453 | |||
Cat.No | ABC-TC0656 | Species | Human | |
Size/Quantity | 1 vial | Biosafety Level | 1 | |
Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
Description | MDA-MB-453 cells were derived in 1976 from a female patient with metastatic breast cancer. These cells have a deletion mutation in the p53 gene, resulting in the absence of the p53 protein. They exhibit aneuploidy, with abnormal numbers of chromosomes, including the absence or under-representation of certain normal chromosomes. Marker chromosomes, with structural abnormalities, are also present. Over time, the cell population has transitioned from near-diploid to tetraploid. MDA-MB-453 cells overexpress fibroblast growth factor (FGF) receptors. Overall, these cells represent a breast cancer cell line with distinct genetic, chromosomal, and receptor expression characteristics. Why choose MDA-MB-453 from AcceGen? Our MDA-MB-453 cell product is sterile, being negative for bacterial, fungal, mycoplasma, and human pathogen contamination. It ensures high quality, viability, and adheres to stringent production standards. The cells exhibit a healthy morphology, and their identity is confirmed using Short Tandem Repeat (STR) analysis. | |||
Source Organ | Breast | |||
Recommended Medium And Supplement | L-15 Medium + 10% FBS | |||
Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). | |||
Application | FOR RESEARCH USE ONLY MDA-MB-453 cells have diverse applications in breast cancer research. | |||
Growth Conditions | 37 ℃ | |||
Cell Type | Epithelial | |||
Growth Mode | Adherent | |||
Product Type | Human Breast Cancer Cell Lines | |||
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