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MDA-MB-231

Product Name

MDA-MB-231

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Product Code

MDA_MB_231; MDA-MB 231; MDA.MB.231; MDA MB 231; MDA MB231; MDA Mb231; MDA-MB231; MDAMB-231; MDAMB231; MDA-231; MDA-231P; MDA231; MDA231-BRE; MB231; MD Anderson-Metastatic Breast-231

Cat.No

ABC-TC0651

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

MDA-MB-231 is an epithelial-like breast cancer cell line originating from pleural effusions of a Caucasian breast cancer patient. It exhibits aneuploidy with a near-triploid range of chromosome counts (modal number = 64, range = 52 to 68). This cell line lacks normal chromosomes N8 and N15 and contains eleven stable rearranged marker chromosomes, along with unassignable chromosomes. Trisomy is observed in most autosomes. The MDA-MB-231 cells appear spindle-shaped, elongated, and thin when reaching subconfluence, while some cells retain a rounded morphology in culture.

 

Why choose MDA-MB-231 from AcceGen?

Choosing MDA-MB-231 from AcceGen offers several advantages. The cell line is characterized by high viability. It is incubated under optimal and sterile conditions by professional operators, ensuring its optimal growth and performance. Moreover, AcceGen implements rigorous quality control measures, guaranteeing the reliability and consistency of the MDA-MB-231 cell line for research and experimental purposes.

Disease

Breast Cancer

Source Organ

Breast

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The MDA-MB-231 cell line has several valuable applications in cancer research. It can be used to establish a xenograft model, forming poorly differentiated adenocarcinoma in ALS-treated BALB/c mice or nude mice. This cell line is particularly useful for studying cancer metastasis and investigating the impact of potential inhibitors on human breast cancer cells. Additionally, researchers can explore its efficacy in inducing apoptosis and evaluate its anticancer activities. The versatility of MDA-MB-231 makes it an important tool for advancing our understanding of breast cancer and developing therapeutic strategies.

Growth Conditions

37 ℃

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Human Breast Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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