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Immortalized Human Fibroblast-Like Synoviocyte

Product Name

Immortalized Human Fibroblast-Like Synoviocyte

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1 vial

Biosafety Level


Shipping Info

Dry Ice


Liquid Nitrogen


Immortalized Human Fibroblast-Like Synoviocytes are derived by immortalizing primary human synoviocytes obtained from healthy synovial tissue through the introduction of SV40 Large T antigen. As the predominant cell type in normal synovial tissue, Human Fibroblast-Like Synoviocytes constitute the synovial lining layer, playing a crucial role in joint health. Responsible for synthesizing synovial fluid, these synoviocytes facilitate absorption in the joint cavity and regulate blood/synovial fluid exchanges. Notably, they exhibit characteristics such as anchorage-independent growth and the secretion of various effector molecules, contributing to inflammation and joint destruction.


Why choose Immortalized Human Fibroblast-Like Synoviocyte from AcceGen?

AcceGen’s Immortalized Human Fibroblast-Like Synoviocytes (IM-HS) exhibit exceptional features, boasting high viability and quality. Each vial contains over 1 million viable cells, ensuring robust and reliable experimental outcomes. AcceGen further enhances the user experience by providing optimized medium and reagents, rigorously quality tested as a global solution to maximize the performance of in vitro IM-HS culture.



Source Organ


Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).



Immortalized Human Fibroblast-Like Synoviocytes offer a valuable cellular model for investigating synoviocyte physiology and the pathogenesis of joint diseases. Serving as a platform to explore synovial tissue organization and morphogenesis, these cells provide crucial insights and represent a potential therapeutic target. Moreover, their utility extends to the establishment of in vitro disease models for high throughput and high content screening, enhancing the efficiency of research focused on understanding and treating various conditions affecting the joints.

Growth Conditions

37 ℃, 5% CO2

Cell Type


Growth Mode


Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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