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MKN-45 |
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| Product Name |
MKN-45 |
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| Price | Get Quote | |||
| Product Code | MKN-45; MKN 45 |
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| Cat.No |
ABC-TC0687 |
Species |
Human |
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| Size/Quantity |
1 vial |
Biosafety Level |
1 |
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| Shipping Info |
Dry Ice |
Storage |
Liquid Nitrogen |
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| Description |
MKN-45 is a human gastric cancer cell line derived from poorly differentiated gastric adenocarcinoma. MKN-45 cells have been used extensively in gastric cancer development study and therapeutic agent assessment. MKN-45 gastric cancer cells express wild-type p53 and are characterized by homozygous deletion of p16CDKN2/MTS1/INK4A and p15MTS2, as well as amplification of c-met oncogene and promoter mutation of E-cadherin. MKN-45 cells exhibit both normal and metaplastic gastric mucosa phenotype with preserved differentiation capacity. Why choose MKN-45 from AcceGen? MKN-45 is derived from poorly differentiated gastric adenocarcinoma of a 62-year-old woman. Cells are cryopreserved to ensure the best viability. Each vial contains more than 1×10^6 cells in 1ml volume. MKN-45 cells are characterized by spindle-shaped or oval-shaped morphology and present a hypertriploid karyotype with 8% polyploidy. Subculture cells at a split ratio of 1:3 to 1:5 every 5-10 days using trypsin/EDTA. |
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| Source Organ | Liver |
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| Quality Control | All cell lots test negative for HIV-1, HBV, HCV, mycoplasma, yeast, fungi, and other pathogens. |
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| Recommended Medium And Supplement | RPMI 1640 + 10% FBS |
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| Citation Guide |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). |
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| Application | For research use only MKN-45 cells provide a useful model for studying the biology and characteristic of gastric cancer. They can also be used to screen for potential drugs or underlying mechanism of gastric cancer and the immunological pathway associated with it. |
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| Key Features | – Backed by AcceGen advanced technology – Cryopreserved for highest viability and plating efficiency – Quality-guaranteed for accurate results – Timely technical support for best experimental outcomes |
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| Growth Conditions | 37 ℃, 5% CO2 |
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| Product Type |
Human Gastric Cancer Cell Lines |
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| Product Image |
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